Otiprio Side Effects

Generic name: ciprofloxacin otic

Medically reviewed by Drugs.com. Last updated on Apr 2, 2025.

Note: This document provides detailed information about Otiprio Side Effects associated with ciprofloxacin otic. Some dosage forms listed on this page may not apply specifically to the brand name Otiprio.

Applies to ciprofloxacin otic: intratympanic suspension.

Other dosage forms:

• otic solution

Serious side effects of Otiprio

Along with its needed effects, ciprofloxacin otic (the active ingredient contained in Otiprio) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ciprofloxacin otic:

Less common side effects

• fever
• headache
• muscle aches
• sore throat
• stuffy or runny nose
• unusual tiredness or weakness

Other side effects of Otiprio

Some side effects of ciprofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

• irritability

For healthcare professionals

Applies to ciprofloxacin otic: otic solution, otic suspension.

General adverse events

The most commonly reported side effects included application site pain, ear pruritus, and headache.^[Ref]

Other

• Common (1% to 10%): Ear pruritus, ear pain, ear discomfort/stinging, otitis media, ear infection (fungal; otomycosis)/fungal ear superinfection
• Postmarketing reports: Crying, ear congestion, otorrhea, pyrexia^[Ref]

Nervous system

• Common (1% to 10%): Headache/cephalea, dizziness, vertigo, dysgeusia/bitter taste
• Uncommon (0.1% to 1%): Tinnitus^[Ref]

Psychiatric

• Common (1% to 10%): Irritability^[Ref]

Respiratory

• Common (1% to 10%): Nasopharyngitis, rhinorrhea^[Ref]

Local

• Common (1% to 10%): Mild local intolerance, application site pain^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Dermatitis

Locally-applied fluoroquinolones:

• Very rare (less than 0.01%): Toxic epidermolysis, exfoliative dermatitis, generalized rash, Stevens-Johnson syndrome, urticaria

Hypersensitivity

• Frequency not reported: Allergic reaction

Systemic quinolone therapy:

• Frequency not reported: Serious and sometimes fatal hypersensitivity (anaphylactic) reactions (some accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal/facial edema, dyspnea, urticaria, itching)

Musculoskeletal

Systemic fluoroquinolones:

• Frequency not reported: Tendon rupture (e.g., shoulder, hand, Achilles)

Frequently asked questions

• What is Otiprio used for?

Further information

Otiprio side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer