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Otiprio Ear Drops Dosage

Generic name: CIPROFLOXACIN 6mg in 1mL
Dosage form: otic suspension

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

Dosage and Important Administration Instructions

  • OTIPRIO is for intratympanic administration only.
  • OTIPRIO is intended for single-patient use, discard unused portion.
  • Administer OTIPRIO as a single intratympanic administration of one 0.1 mL (6 mg) dose into each affected ear, following suctioning of middle ear effusion.

Preparation of OTIPRIO

Directions for OTIPRIO dose preparation and handling is illustrated in Figure 1 below.

Figure 1: Directions for OTIPRIO Dose Preparation

STEP 1 Preparation

Materials needed:

1 vial of OTIPRIO (enough for 2 doses); Two 1mL luer lock syringers;
Two 18G-21G preparation needles; Two 20-24G, 2-3 inch blunt, flexible administration needles; Alcohol pads; Optional: ice pack and drape to keep OTIPRIO vial cold

Keep product cold during preparation. If OTIPRIO thickens during
preparation, place the vial back in refrigeration.

figure 1

To keep the vial cold during shaking, hold the OTIPRIO vial by the
aluminium seal to prevent gelation. Shake the vial for 5 to 8 seconds to
mix well until a visually homogenous suspension is obtained.

Always hold the vial by the aluminium seal to prevent gelation.
figure 2

Using an 18-21G needle, withdraw 0.3 mL of the suspension into the 1 mL
figure 3
STEP 4 Replace with the Aldministration Needle

Replace the needle with a 20-24G, 2-3 inch blunt, flexible needle to be used for administration.
figure 4
STEP 5 Priming the Syringe

Prime the needle leaving a dose of 0.1 ml (0.1 cc).
figure 5
STEP 6 Preparing Second Dose for Bilateral Administartion Only

Repeat Steps 3, 4, and 5 using the same vial to prepare a second syringe
for the other ear and dispose of the vial.

Use a different syringe for each ear.

After preparation, syringes can be kept at room temperature or in the
refrigerator prior to administration.

Keep syringes on their side.

Discard syringes if not administered in 3 hours.
figure 6