OptiMARK Side Effects
Generic Name: gadoversetamide
Note: This page contains side effects data for the generic drug gadoversetamide. It is possible that some of the dosage forms included below may not apply to the brand name OptiMARK.
More frequent side effects include: nephrogenic systemic fibrosis. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to gadoversetamide: intravenous solution
Get emergency medical help if you have any of these signs of an allergic reaction while taking gadoversetamide (the active ingredient contained in OptiMARK) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
urinating less than usual or not at all;
drowsiness, confusion, mood changes, increased thirst, loss of appetite;
swelling, weight gain, feeling short of breath; or
fast, uneven heart rate.
Less serious side effects of gadoversetamide may include:
flushing (warmth, redness, or tingly feeling);
unusual or unpleasant taste in your mouth;
numbness, burning pain, or tingling in your hands or feet; or
cold feeling, warmth, pain, bruising, swelling, or burning where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to gadoversetamide: intravenous solution
Nervous system side effects have included headache, dizziness, paresthesia, agitation, anxiety, confusion, depersonalization, dystonia, hallucinations, hypertonia, hypesthesia, nervousness, somnolence, tremor, hyperacusis, parosmia, tinnitus, seizure, and vertigo.[Ref]
Cardiovascular side effects have included vasodilatation, arrhythmia, chest pain, hypertension, hypotension, pallor, palpitation, syncope, tachycardia, and vasospasm.[Ref]
Gastrointestinal side effects have included taste perversion, nausea, anorexia, increased appetite, constipation, dry mouth, dysphagia, eructation, flatulence, increased salivation, thirst, and vomiting.[Ref]
Ocular side effects have included diplopia, amblyopia, and conjunctivitis.[Ref]
Respiratory side effects have included asthma, cough, dyspnea, epistaxis, hemoptysis, laryngismus, pharyngitis, sinusitis, and voice alteration.[Ref]
Local side effects have included application site reaction, injection site edema and inflammation.[Ref]
Dermatologic side effects have included erythema multiforme, pruritus, macular papular rash, vesicullous bullous rash, skin dry, thrombophlebitis, and urticaria.[Ref]
Musculoskeletal side effects have included arthralgia, leg cramps, myalgia, myasthenia, and spasm.[Ref]
Genitourinary side effects have included dysuria, oliguria, and urine frequency.[Ref]
Metabolic side effects have included increased creatinine, edema, hypercalcemia, hyperglycemia, hypoglycemia, and hyponatremia.[Ref]
Hematologic side effects have included thrombocytopenia.[Ref]
Hypersensitivity side effects have included allergic reaction, facial edema, fever, flu-like syndrome, malaise, mucous membrane discharge, neck rigidity, neck pain, pelvic pain, and increased sweating.[Ref]
1. "Product Information. OptiMARK (gadoversetamide)." Mallinckrodt Medical Inc, St. Louis, MO.
It is possible that some side effects of OptiMARK may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about OptiMARK (gadoversetamide)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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