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Mitomycin ophthalmic Side Effects

For the Consumer

Applies to mitomycin ophthalmic: topical application pad, topical application powder for solution

In addition to its needed effects, some unwanted effects may be caused by mitomycin ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking mitomycin ophthalmic, check with your doctor or nurse immediately:

More common:
  • Blindness
  • blurred vision or other change in vision
  • decreased vision
  • dislocated eye implants
  • eye pain
  • eye redness
  • flashes of light or floaters in vision
  • headache
  • irritation or inflammation of the eye
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • tearing of the eyes

Minor Side Effects

Some of the side effects that can occur with mitomycin ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Opening of the surgical wound
  • raising of the upper eyelid
  • sensitivity of the eyes to light
  • throbbing pain

For Healthcare Professionals

Applies to mitomycin ophthalmic: ophthalmic kit


The most commonly reported side effects include blebitis, corneal changes, and other localized reactions.[Ref]


Frequency not reported: Blebitis, bleb ulceration, chronic bleb leak, encapsulated/cystic bleb, bleb-related infection, conjunctival necrosis, thin-walled bleb, Descemet's detachment, induced astigmatism, corneal epithelial damage, superficial punctate keratitis, endophthalmitis, hypotony, choroidal reaction, choroidal detachment, choroidal reactions, choroidal detachment, choroidal effusion, serious choroidal detachment, suprachoroidal hemorrhage, hypotony maculopathy, presence of supraciliochoroidal effusion, iritis, cataract development, capsular constriction, posterior synechiae, retinal pigment epithelial tear, serous/rhegatogenous retinal detachment, hyphema, vitreal/retinal/subconjunctival/disk hemorrhage, macular edema, sclera thinning/ulceration, intraocular lens capture, disk swelling, malignant glaucoma, lacrimal drainage system obstruction, ciliary block, corneal vascularization, decreased visual acuity, cystic conjunctival degeneration, upper eyelid retraction, dislocated implants, severe loss of vision, hemiretinal/central retinal vein occlusion[Ref]


Frequency not reported: Wound dehiscence/scleral wound dehiscence[Ref]


Frequency not reported: Blood clot[Ref]


1. "Product Information. Mitosol (mitoMYcin ophthalmic)." Mobius Therapeutics, St. Loius, MO.

Not all side effects for mitomycin ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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