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Mitomycin ophthalmic Side Effects

Medically reviewed by Last updated on Apr 24, 2022.

For the Consumer

Applies to mitomycin ophthalmic: ophthalmic powder for solution

Side effects requiring immediate medical attention

Along with its needed effects, mitomycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking mitomycin ophthalmic:

Incidence not known

  • Blindness
  • blurred vision
  • decreased vision or any change in vision
  • dislocated eye implants
  • eye pain, redness, irritation, or inflammation
  • flashes of light or floaters in vision
  • headache
  • red or bloodshot eye
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • tearing of the eyes

Side effects not requiring immediate medical attention

Some side effects of mitomycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Opening of the surgical wound
  • raising of the upper eyelid
  • sensitivity of the eyes to light
  • throbbing pain

For Healthcare Professionals

Applies to mitomycin ophthalmic: ophthalmic kit


The most commonly reported side effects include blebitis, corneal changes, and other localized reactions.[Ref]


Frequency not reported: Blebitis, bleb ulceration, chronic bleb leak, encapsulated/cystic bleb, bleb-related infection, conjunctival necrosis, thin-walled bleb, Descemet's detachment, induced astigmatism, corneal epithelial damage, superficial punctate keratitis, endophthalmitis, hypotony, choroidal reaction, choroidal detachment, choroidal reactions, choroidal detachment, choroidal effusion, serious choroidal detachment, suprachoroidal hemorrhage, hypotony maculopathy, presence of supraciliochoroidal effusion, iritis, cataract development, capsular constriction, posterior synechiae, retinal pigment epithelial tear, serous/rhegatogenous retinal detachment, hyphema, vitreal/retinal/subconjunctival/disk hemorrhage, macular edema, sclera thinning/ulceration, intraocular lens capture, disk swelling, malignant glaucoma, lacrimal drainage system obstruction, ciliary block, corneal vascularization, decreased visual acuity, cystic conjunctival degeneration, upper eyelid retraction, dislocated implants, severe loss of vision, hemiretinal/central retinal vein occlusion[Ref]


Frequency not reported: Wound dehiscence/scleral wound dehiscence[Ref]


Frequency not reported: Blood clot[Ref]


1. "Product Information. Mitosol (mitomycin ophthalmic)." Mobius Therapeutics (2012):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.