Mitomycin Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Dec 3, 2024.

Usual Adult Dose for Glaucoma

• Usual dose: 0.2 mg applied with saturated sponges (provided in the kit) equally to the treatment area with surgical forceps
• Duration of therapy: 2 minutes

Comments:

• This drug should not be administered intraocularly.
• After 2 minutes, sponges and preparation materials should be discarded in a chemotherapy waste bag.

Use: As an adjunct to ab externo glaucoma surgery

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Sponges should be fully saturated with the entire amount prior to application, and should be arranged in a single layer on the treatment area.
• Forceps may be used to hold the sponges to the treatment area.

Storage requirements:

• Protect from light.
• Reconstituted product may be stored at room temperature for up to 1 hour.

Reconstitution/preparation techniques:

• This drug should be reconstituted with 1 mL of sterile water for injection, then the vial should be shaken to dissolve.
• If dissolution does not occur immediately, the vial should be allow to stand at room temperature until dissolution occurs.

Patient advice:

• Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
• Patients should be cautioned of the potential for complications associated with toxicity from this drug.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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