Generic name: mitomycin (mye-toe-MYE-sin)
Drug class: Miscellaneous ophthalmic agents
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Ophthalmologic Agent
Medically reviewed by Drugs.com. Last updated on Jun 12, 2021.
Uses for mitomycin
Mitomycin topical eye solution is used to help in glaucoma surgery. Mitomycin belongs to the group of medicines called antimetabolites.
Mitomycin is to be applied only by or under the direct supervision of your doctor.
Before using mitomycin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For mitomycin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to mitomycin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of mitomycin topical eye solution in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of mitomycin topical eye solution in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving mitomycin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using mitomycin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of mitomycin. Make sure you tell your doctor if you have any other medical problems, especially:
- Cataracts or
- Lens implant (eg, phakic intraocular lens)—Use with caution. May increase risk for serious side effects.
Proper use of mitomycin
A doctor or other trained health professional will apply mitomycin to your eyes using sponges during glaucoma filtration surgery.
Precautions while using mitomycin
Your eye doctor will check your eyes closely to make sure it is working properly and is not causing unwanted effects.
Receiving mitomycin while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before receiving mitomycin. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while receiving the medicine, tell your doctor right away.
Mitomycin may increase the risk of cataracts. Tell your doctor right away if you have blindness, blurred vision, or decreased vision.
Tell your doctor right away if you have decreased vision or any changes in your vision. These could be symptoms of hypotony (decreased tension or pressure in the eye).
Mitomycin side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Incidence not known
- blurred vision
- decreased vision or any change in vision
- dislocated eye implants
- eye pain, redness, irritation, or inflammation
- flashes of light or floaters in vision
- red or bloodshot eye
- seeing flashes or sparks of light
- seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
- tearing of the eyes
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Opening of the surgical wound
- raising of the upper eyelid
- sensitivity of the eyes to light
- throbbing pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
More about mitomycin ophthalmic
- Side Effects
- During Pregnancy
- Dosage Information
- En Español
- Drug class: miscellaneous ophthalmic agents
- Other brands
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.