Metamucil MultiHealth Fiber Side Effects
Generic name: psyllium
Medically reviewed by Drugs.com. Last updated on Oct 6, 2022.
Note: This document contains side effect information about psyllium. Some dosage forms listed on this page may not apply to the brand name Metamucil MultiHealth Fiber.
Applies to psyllium: oral capsule, oral packet, oral powder, oral wafer.
Serious side effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Trouble swallowing.
Other side effects
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to psyllium: oral capsule, oral powder for reconstitution, oral wafer.
Hypersensitivity side effects have been reported rarely. They have included sensitization from inhalation of fine dust particles dispersed into the air as the product is mixed or poured.[Ref]
While hypersensitivity reactions may be severe, they are most frequently reported by workers in the pharmaceutical firms that manufacture the drug. This is because when it is mixed or poured, fine dust particles are readily dispersed into the air and can then be inhaled and cause sensitization. Orally ingested psyllium seems less likely to induce sensitization.[Ref]
Gastrointestinal side effects have included several cases of esophageal impaction and duodenal bezoars in patients receiving a bulk laxative product containing 82% psyllium (the active ingredient contained in Metamucil MultiHealth Fiber) and 18% senna (commercially available as Perdiem Overnight Relief). Other gastrointestinal side effects have included nausea, intestinal gas, cramps, mild diarrhea, rectal pain, constipation, and irritation.[Ref]
Hematologic side effects have included a case of eosinophilia.[Ref]
More about Metamucil MultiHealth Fiber (psyllium)
Related treatment guides
1. Gillespie BF, Rathbun FJ "Adverse effects of psyllium." CMAJ 146 (1992): 16-7
2. Anderson JW, Floore TL, Geil PB, O'Neal DS, Balm TK "Hypocholesterolemic effects of different bulk-forming hydrophilic fibers as adjuncts to dietary therapy in mild to moderat hypercholesterolemia." Arch Intern Med 151 (1991): 1597-602
3. Angueira C, Kadakia S "Esophageal and duodenal bezoars from Perdiem [letter]." Gastrointest Endosc 39 (1993): 110-1
4. Stoy DB, LaRosa JC, Brewer BK, Mackey M, Meusing RA "Cholesterol-lowering effects of ready-to-eat cereal containing psyllium." J Am Diet Assoc 93 (1993): 910-2
5. Schneider RP "Perdiem causes esophageal impaction and bezoars." South Med J 82 (1989): 1449-50
6. Nelson AM, Taubin HL, Frank HD "Eosinophilia associated with psyllium hydrophilic colloid ingestion [letter." JAMA 243 (1980): 329-30
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.