Skip to Content

Mechlorethamine topical Side Effects

For the Consumer

Applies to mechlorethamine topical: topical application gel/jelly

In addition to its needed effects, some unwanted effects may be caused by mechlorethamine topical. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking mechlorethamine topical:

More common:
  • Blistering, crusting, irritation, itching, or reddening of the skin
  • cracked, dry, scaly skin
  • pain, swelling, tenderness, or warmth on the skin

Minor Side Effects

Some of the side effects that can occur with mechlorethamine topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Darkening of the skin

For Healthcare Professionals

Applies to mechlorethamine topical: topical gel

Dermatologic

Very common (10% or more): Dermatitis (56%), pruritus (20%), bacterial skin infection (11%)
Common (1% to 10%): Skin ulceration or blistering (6%), skin hyperpigmentation (5%)[Ref]

Hematologic

Very common (10% or more): Reductions in hemoglobin, neutrophil count, or platelet count (13%)[Ref]

Oncologic

Common (1% to 10%): Non-melanoma skin cancer (4%)[Ref]

References

1. "Product Information. Valchlor (mechlorethamine topical)." Ceptaris Therapeutics, Malvern, PA.

Not all side effects for mechlorethamine topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide