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Lymphocyte immune globulin, anti-thy (equine) Side Effects

For the Consumer

Applies to lymphocyte immune globulin, anti-thy (equine): parenteral concentrate for injection

Side effects include:

Renal allotransplantation: Fever, chills, leukopenia, thrombocytopenia, dermatologic reactions (rash, pruritus, urticaria, wheal and flare).

Aplastic anemia: Fever, chills, skin reactions, arthralgia, headache, myalgia, nausea, chest pain, phlebitis, serum sickness.

For Healthcare Professionals

Applies to lymphocyte immune globulin, anti-thy (equine): intravenous solution

General

General side effects have included fever, chills, herpes simplex reactivation, localized infection, systemic infection, possible serum sickness, lymphadenopathy, post-cervical lymphadenopathy, tender lymph nodes and night sweats.[Ref]

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis.[Ref]

Dermatologic

Dermatologic side effects have included rash, pruritus, urticaria, wheal, flare, toxic epidermal necrosis and wound dehiscence.[Ref]

Musculoskeletal

Musculoskeletal side effects have included arthralgia, chest, flank or back pain, leg pains, myalgia, joint stiffness, muscle ache, burning soles, burning palms, and foot sole pain.[Ref]

Gastrointestinal

Gastrointestinal side effects have included GI bleeding or perforation, hiccoughs, epigastric pain, stomach pain, diarrhea, abdominal pain, stomatitis, laryngospasm, nausea and vomiting.[Ref]

Cardiovascular

Cardiovascular side effects have included hypertension, hypotension, tachycardia, congestive heart failure, edema, vasculitis and deep vein thrombosis, thrombophlebitis, clotted A-V fistula, myocarditis, cardiac irregularity, bradycardia, renal artery thrombosis, and iliac vein obstruction.[Ref]

Hematologic

Hematologic side effects have included thrombocytopenia, leukopenia, hepatosplenomegaly, neutropenia or granulocytopenia, anemia and thrombophlebitis.[Ref]

Respiratory

Respiratory side effects have included respiratory distress, dyspnea, apnea, pulmonary edema, bilateral pleural effusion, laryngospasm/edema, cough and sore mouth/throat.[Ref]

Nervous system

Nervous system side effects have included headache, dizziness, paresthesia, weakness or faintness, agitation/lethargy, listlessness, lightheadedness, seizures, malaise, confusion or disorientation, abnormal involuntary movement or tremor, possible encephalitis or post viral encephalopathy and rigidity.[Ref]

Local

Local side effects have included pain at the infusion site.[Ref]

Renal

Renal side effects have included proteinuria.[Ref]

Ocular

Ocular side effects have included periorbital edema.[Ref]

Metabolic

Metabolic side effects have included hyperglycemia.[Ref]

Hepatic

Hepatic side effects have included hepatosplenomegaly.[Ref]

References

1. "Product Information. Atgam (lymphocyte immune globulin, anti-thy (equine))." Pfizer U.S. Pharmaceuticals Group, New York, NY.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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