Ioxilan Side Effects

Applies to ioxilan: injectable solution.

General adverse events

General side effects including headache (3.6%), fever (1.7%), chills (0.6%), asthenia, chest and back pain, edema of the neck, facial edema, pain, and peripheral edema have been reported.^[Ref]

Cardiovascular

• Common (1% to 10%): Angina pectoris (1.3%), hypertension (1.1%)
• Uncommon (0.1% to 1%): Bradycardia, hypotension, atrial fibrillation, syncope, tachycardia, vasodilation, ventricular extrasystole^[Ref]

Severe life-threatening cardiovascular reactions and fatalities have occurred. Most deaths occur during injection or 5 to 10 minutes later; the main feature being cardiac arrest with cardiovascular disease as the main aggravating factor.^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea (1.5%)
• Uncommon (0.1% to 1%): Diarrhea, nausea with vomiting, constipation, dyspepsia, dysphagia, gastrointestinal hemorrhage, ileus^[Ref]

Nervous system

• Common (1% to 10%): Headache (3.6%)
• Uncommon (0.1% to 1%): Dizziness, hypotonia, nystagmus, paresthesia, somnolence, vertigo, taste perversion^[Ref]

Other

• Common (1% to 10%): Fever (1.7%)
• Uncommon (0.1% to 1%): Chills, asthenia, edema of the neck, facial edema, pain, peripheral edema^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Urticaria, rash, pruritus, sweating^[Ref]

Endocrine

• Uncommon (0.1% to 1%): Hypothyroidism or transient thyroid suppression^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Anuria, dysuria, hematuria, urinary tract infection, urination impairment^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Liver failure^[Ref]

Hypersensitivity

• Uncommon (0.1% to 1%): Allergic reaction^[Ref]

The reported incidence of adverse reactions to contrast agents in patients with a history of allergy is twice that of the general population. Patients with a history of previous reactions to a contrast agent are three times more susceptible than other patients. However, sensitivity to contrast agents does not appear to increase with repeated examinations.^[Ref]

Local

• Uncommon (0.1% to 1%): Hematoma at the injection site^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Anorexia^[Ref]

Musculoskeletal

• Uncommon (0.1% to 1%): Chest and back pain^[Ref]

Ocular

• Uncommon (0.1% to 1%): Amblyopia, conjunctivitis, vision abnormality^[Ref]

Renal

• Uncommon (0.1% to 1%): Kidney failure^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Dyspnea, pharyngitis, rhinitis
• Postmarketing reports: Bronchospasm^[Ref]

See also:

Further information

Ioxilan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer