Ioxilan Side Effects

Applies to ioxilan: injectable solution.

General

General side effects including headache (3.6%), fever (1.7%), chills (0.6%), asthenia, chest and back pain, edema of the neck, facial edema, pain, and peripheral edema have been reported.^[Ref]

Cardiovascular

• Common (1% to 10%): Angina pectoris (1.3%), hypertension (1.1%)
• Uncommon (0.1% to 1%): Bradycardia, hypotension, atrial fibrillation, syncope, tachycardia, vasodilation, ventricular extrasystole^[Ref]

Severe life-threatening cardiovascular reactions and fatalities have occurred. Most deaths occur during injection or 5 to 10 minutes later; the main feature being cardiac arrest with cardiovascular disease as the main aggravating factor.^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea (1.5%)
• Uncommon (0.1% to 1%): Diarrhea, nausea with vomiting, constipation, dyspepsia, dysphagia, gastrointestinal hemorrhage, ileus^[Ref]

Nervous system

• Common (1% to 10%): Headache (3.6%)
• Uncommon (0.1% to 1%): Dizziness, hypotonia, nystagmus, paresthesia, somnolence, vertigo, taste perversion^[Ref]

Other

• Common (1% to 10%): Fever (1.7%)
• Uncommon (0.1% to 1%): Chills, asthenia, edema of the neck, facial edema, pain, peripheral edema^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Urticaria, rash, pruritus, sweating^[Ref]

Endocrine

• Uncommon (0.1% to 1%): Hypothyroidism or transient thyroid suppression^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Anuria, dysuria, hematuria, urinary tract infection, urination impairment^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Liver failure^[Ref]

Hypersensitivity

• Uncommon (0.1% to 1%): Allergic reaction^[Ref]

The reported incidence of adverse reactions to contrast agents in patients with a history of allergy is twice that of the general population. Patients with a history of previous reactions to a contrast agent are three times more susceptible than other patients. However, sensitivity to contrast agents does not appear to increase with repeated examinations.^[Ref]

Local

• Uncommon (0.1% to 1%): Hematoma at the injection site^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Anorexia^[Ref]

Musculoskeletal

• Uncommon (0.1% to 1%): Chest and back pain^[Ref]

Ocular

• Uncommon (0.1% to 1%): Amblyopia, conjunctivitis, vision abnormality^[Ref]

Renal

• Uncommon (0.1% to 1%): Kidney failure^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Dyspnea, pharyngitis, rhinitis
• Postmarketing reports: Bronchospasm^[Ref]

Further information

Ioxilan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer