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Hydrocortisone / urea topical Side Effects

Applies to hydrocortisone / urea topical: topical cream


Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.[Ref]


Local side effects associated with topical hydrocortisone have included burning, itching, or irritation, especially if applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.[Ref]


1. "Product Information. Carmol HC (hydrocortisone-urea topical)." Bradley Pharmaceuticals Inc, Fairfield, NJ.

Not all side effects for hydrocortisone / urea topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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