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Histex IE Side Effects

Generic Name: carbinoxamine

Note: This page contains information about the side effects of carbinoxamine. Some of the dosage forms included on this document may not apply to the brand name Histex IE.

For the Consumer

Applies to carbinoxamine: oral capsule extended release, oral liquid, oral solution, oral suspension, oral suspension extended release, oral tablet, oral tablet extended release

In addition to its needed effects, some unwanted effects may be caused by carbinoxamine (the active ingredient contained in Histex IE). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking carbinoxamine:

Incidence not known:
  • Blurred vision
  • chills
  • confusion
  • cough
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult or painful urination
  • difficulty in passing urine (dribbling)
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, irregular, pounding, or racing heartbeat or pulse
  • hives or welts
  • itching
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rash
  • redness of the skin
  • skin rash
  • sweating
  • tightness in the chest
  • unusual tiredness or weakness

If any of the following symptoms of overdose occur while taking carbinoxamine, get emergency help immediately:

Symptoms of overdose:
  • Agitation
  • anxiety
  • bloating
  • convulsions
  • diarrhea
  • difficulty with sleeping
  • disorientation
  • dizziness
  • drowsiness to profound coma
  • dry mouth
  • feeling of warmth
  • fixed and enlarged pupils
  • gas
  • headache
  • lethargy
  • lightheadedness
  • loss of appetite
  • nausea
  • redness of the face, neck, arms, and occasionally, upper chest
  • seeing, hearing, or feeling things that are not there
  • stomach pain
  • tightness of the chest
  • trouble breathing
  • vomiting

Minor Side Effects

Some of the side effects that can occur with carbinoxamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Disturbed coordination
  • drowsiness
  • sleepiness
Incidence not known:
  • Back, leg, or stomach pains
  • black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chills
  • confusion
  • continuing ringing or buzzing or other unexplained noise in the ears
  • cough or hoarseness
  • dark urine
  • difficulty breathing
  • difficulty having a bowel movement (stool)
  • dizziness or lightheadedness
  • double vision
  • dry mouth, nose, and throat
  • feeling excited
  • feeling of constant movement of self or surroundings
  • fever with or without chills
  • general body swelling
  • general feeling of tiredness or weakness
  • headache
  • hearing loss
  • increased sensitivity of the skin to sunlight
  • itching
  • loss of appetite
  • lower back or side pain
  • nosebleeds
  • pale skin
  • pinpoint red spots on the skin
  • redness or other discoloration of the skin
  • restlessness
  • seeing double
  • seizures
  • sensation of spinning
  • severe sunburn
  • shakiness in the legs, arms, hands, or feet
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • trembling or shaking of the hands or feet
  • trouble sleeping
  • unusual bleeding or bruising
  • weight loss
  • yellowing of the eyes or skin

For Healthcare Professionals

Applies to carbinoxamine: oral capsule extended release, oral liquid, oral suspension, oral suspension extended release, oral tablet, oral tablet extended release

Nervous system

Nervous system side effects have included sedation, dizziness, headache, and nervousness.[Ref]


Ocular side effects have included diplopia.[Ref]


Gastrointestinal side effects have included vomiting, diarrhea, dry mouth, nausea, heartburn, and anorexia.[Ref]


Other side effects have included weakness.[Ref]


Genitourinary side effects have included polyuria.[Ref]


1. "Product Information. Palgic (carbinoxamine)." Pamlab LLC, Mandeville, LA.

2. "Product Information. Histex I/E (carbinoxamine)." Teamm Pharmaceuticals Inc, Morrisville, NC.

3. "Product Information. Histex PD (carbinoxamine)." Andrx Pharmaceuticals, Davie, FL.

4. "Product Information. Pediatex (carbinoxamine)." Zyber Pharmaceuticals Inc, Gonzales, LA.

5. "Product Information. Histex Pd 12 (carbinoxamine)." Teamm Pharmaceuticals Inc, Morrisville, NC.

6. "Product Information. Histex CT (carbinoxamine)." Andrx Pharmaceuticals, Davie, FL.

Not all side effects for Histex IE may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.