GP 500 Side Effects
Generic name: guaifenesin / pseudoephedrine
Medically reviewed by Drugs.com. Last updated on Apr 23, 2024.
Note: This document provides detailed information about GP 500 Side Effects associated with guaifenesin / pseudoephedrine. Some dosage forms listed on this page may not apply specifically to the brand name GP 500.
Applies to guaifenesin / pseudoephedrine: oral capsule, oral liquid, oral tablet, oral tablet extended release.
Important warnings
This medicine can cause some serious health issues
Do not use guaifenesin and pseudoephedrine if you have used an MAO inhibitor in the past 14 days.
A dangerous drug interaction could occur.
MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.
Taking more than your recommended dose will not make this medicine more effective, and may cause serious side effects.
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Stop using guaifenesin and pseudoephedrine and call your doctor at once if you have:
-
nervousness, dizziness, sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For healthcare professionals
Applies to guaifenesin / pseudoephedrine: oral capsule, oral capsule extended release, oral liquid, oral syrup, oral tablet, oral tablet chewable, oral tablet extended release.
Cardiovascular
- Frequency not reported: Tachycardia, palpitations, other cardiac dysrhythmias, hypertension[Ref]
Nervous system
Psychiatric
- Frequency not reported: Irritability, tolerance and dependence (with prolonged pseudoephedrine administration), anxiety, restlessness, insomnia, hallucinations (particularly in children), paranoid delusions, sleep disturbance[Ref]
Hypersensitivity
- Frequency not reported: Hypersensitivity reactions, cross-sensitivity with other sympathomimetics[Ref]
Genitourinary
- Frequency not reported: Difficulty in micturition (including urinary retention)[Ref]
Dermatologic
- Frequency not reported: Skin reactions (including rash, sweating), severe skin reactions including acute generalized exanthematous pustulosis (AGEP)[Ref]
Gastrointestinal
Musculoskeletal
- Frequency not reported: Muscular weakness[Ref]
Metabolic
- Frequency not reported: Thirst[Ref]
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
More about GP 500 (guaifenesin / pseudoephedrine)
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
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Further information
GP 500 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.