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Gadopentetate dimeglumine Side Effects

Medically reviewed by Last updated on Oct 15, 2023.

Applies to gadopentetate dimeglumine: injectable solution.


Gadopentetate dimeglumine can cause a life-threatening condition in people with advanced kidney disease. You should not receive this medication if you have kidney disease or if you are on dialysis.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some side effects of gadopentetate dimeglumine may occur up to several days after injection.

Gadopentetate dimeglumine can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

Also call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to gadopentetate dimeglumine: injectable solution.


Cardiovascular side effects have included hypotension, hypertension, arrhythmia, tachycardia, syncope, vasodilation, pallor, nonspecific ECG changes, angina pectoris, death related to myocardial infarction, phlebitis, thrombophlebitis, deep venous thrombophlebitis, and compartment syndrome requiring surgery.[Ref]


Gastrointestinal side effects have included gastrointestinal distress, stomach pain, increased salivation, abdominal pain, vomiting, constipation, thirst, anorexia, dry mouth, and diarrhea.[Ref]

Nervous system

Nervous system side effects have included agitation, anxiety, migraine, nystagmus, drowsiness, stupor, paresthesia, and convulsions.[Ref]


Ocular side effects have included diplopia, conjunctivitis, visual field defect, lacrimation disorder, eye irritation, and eye pain.[Ref]


Respiratory side effects have included throat irritation, rhinorrhea, sneezing, dyspnea, wheezing, laryngismus, cough, and respiratory complaints.[Ref]


Dermatologic side effects have included rash, sweating, pruritus, urticaria, facial edema, erythema multiforme, epidural necrolysis, and pustules.[Ref]


Local side effects have included pain, localized warmth, and burning sensation at the injection site.[Ref]


Hypersensitivity side effects have included substernal chest pain, back pain, fever, weakness, generalized coldness, generalized warmth, localized edema, tiredness, chest tightness, trembling, shivering, tension in the extremities, regional lymphangitis, pelvis pain, and anaphylactoid reactions.[Ref]


Other side effects have included tinnitus and taste abnormalities.[Ref]


1. Product Information. Magnevist (gadopentetate dimeglumine). Berlex Laboratories. 2005.

2. Garcia N, Ramon E, Gonzalez del Valle L, Ruano M, Jimenez E. Importance of a previous allergy to an iodinated contrast agent in the administration of gadopentetate dimeglumine. Ann Pharmacother. 1997;31:374.

3. Tardy B, Guy C, Barral G, Page Y, Ollagnier M, Bertrand JC. Anaphylactic shock induced by intravenous gadopentetate dimeglumine. Lancet. 1992;339:494.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.