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Duraphen II Side Effects

Generic Name: guaifenesin / phenylephrine

Note: This document contains side effect information about guaifenesin / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Duraphen II.

For the Consumer

Applies to guaifenesin / phenylephrine: oral liquid, oral syrup, oral tablet

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Feeling nervous and excitable.
  • Not able to sleep.
  • Feeling sleepy.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to guaifenesin/phenylephrine: oral capsule, oral capsule extended release, oral drops, oral liquid, oral suspension, oral syrup, oral tablet, oral tablet extended release

Cardiovascular

Cardiovascular side effects have included tachycardia, palpitations, arrhythmias, and cardiovascular collapse with hypotension.[Ref]

Nervous system

Nervous system side effects have included central nervous system depression, tremor, headache, dizziness, restlessness, insomnia, and convulsions.[Ref]

Psychiatric

Psychiatric side effects have included fear, nervousness, anxiety, and hallucinations.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.[Ref]

Respiratory

Respiratory side effects have included breathing difficulty.[Ref]

Genitourinary

Genitourinary side effects have included dysuria.[Ref]

Dermatologic

Dermatologic side effects have included pallor.[Ref]

General

General side effects have included weakness.[Ref]

References

1. "Product Information. Duratuss GP (guaifenesin-phenylephrine)." Victory Pharma, San Diego, CA.

2. "Product Information. Duratuss (guaifenesin-phenylephrine)." Victory Pharma, San Diego, CA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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