Donatussin MAX Side Effects
Generic name: carbinoxamine / hydrocodone / phenylephrine
Note: This document provides detailed information about Donatussin MAX Side Effects associated with carbinoxamine / hydrocodone / phenylephrine. Some dosage forms listed on this page may not apply specifically to the brand name Donatussin MAX.
Applies to carbinoxamine/hydrocodone/phenylephrine: oral liquid.
Important warnings
This medicine can cause some serious health issues
Always ask a doctor before giving a cough or cold medicine to a child, even if the medicine label provides dosing instructions for children. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use carbinoxamine, hydrocodone, and phenylephrine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take carbinoxamine, hydrocodone, and phenylephrine before the MAO inhibitor has cleared from your body.
Carbinoxamine, hydrocodone, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can increase some of the side effects of this medication.
Call your doctor if you have a fever, or if your symptoms get worse or do not improve after taking this medicine for 7 days.
Do not take this product for cough caused by smoking, asthma, or emphysema. Do not take this medicine if your cough produces a lot of mucus, unless your doctor has told you to.
Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medicine should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
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seizure (convulsions);
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unusual behavior or hallucinations;
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an irregular or fast heartbeat;
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feeling light-headed, fainting;
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urinating less than usual or not at all;
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wheezing, tightness in your chest;
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fast or pounding heartbeat;
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jaundice (yellowing of the skin or eyes);
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pale skin, easy bruising or bleeding;
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slow or weak breathing; or
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swelling, rapid weight gain.
Continue taking this medication and talk to your doctor if you have any of these less serious side effects:
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drowsiness, dizziness;
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lack of coordination;
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upset stomach, nausea, stomach cramps, or constipation;
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stuffy nose, chest congestion;
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sleep problems (insomnia);
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itchy skin rash;
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decreased hearing or ringing in the ears;
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feeling restless or excited (especially in children);
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dry mouth or nose; or
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blurred vision.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
The hydrocodone in this medication may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in your diet may also help to alleviate constipation.
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
For healthcare professionals
Applies to carbinoxamine / hydrocodone / phenylephrine: oral liquid.
Respiratory adverse events
Respiratory side effects have included respiratory depression and respiratory difficulty.[Ref]
Nervous system
Nervous system side effects have included sedation, dizziness, light-headedness, headache, nervousness, insomnia, hallucinations, tremor, convulsions, and central nervous system depression.[Ref]
Gastrointestinal
Gastrointestinal side effects have included vomiting, constipation, dry mouth, anorexia, and heartburn.[Ref]
Cardiovascular
Cardiovascular side effects have included cardiac arrhythmias, increased heart rate or blood pressure, and pallor.[Ref]
Genitourinary
Genitourinary side effects have included polyuria and dysuria.[Ref]
Ocular
Ocular side effects have included diplopia.[Ref]
Psychiatric
Psychiatric side effects have included euphoria and dysphoria.[Ref]
Dermatologic
Dermatologic side effects have included skin rash and pruritus.[Ref]
References
1. (2005) "Product Information. Excof (carbinoxamine / hydrocodone / phenylephrine)." Stewart-Jackson Pharmaceutical Inc
More about Donatussin MAX (carbinoxamine / hydrocodone / phenylephrine)
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Other formulations
Related treatment guides
Further information
Donatussin MAX side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.