Daybue Side Effects

Generic name: trofinetide

Medically reviewed by Drugs.com. Last updated on Mar 10, 2025.

Note: This document provides detailed information about Daybue Side Effects associated with trofinetide. Some dosage forms listed on this page may not apply specifically to the brand name Daybue.

Applies to trofinetide: oral solution.

Serious side effects of Daybue

Along with its needed effects, trofinetide (the active ingredient contained in Daybue) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trofinetide:

More common side effects

• anxiety
• decreased appetite
• diarrhea
• seizures
• weight loss

Other side effects of Daybue

Some side effects of trofinetide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• fever
• headache
• muscle aches
• sore throat
• stuffy or runny nose
• unusual tiredness or weakness

For healthcare professionals

Applies to trofinetide: oral liquid.

General adverse events

The most common adverse reactions were diarrhea and vomiting.^[Ref]

Gastrointestinal

• Very common (10% or more): Diarrhea (82%), vomiting (29%)^[Ref]

Metabolic

• Common (1% to 10%): Decreased appetite^[Ref]

Nervous system

• Common (1% to 10%): Seizure^[Ref]

Other

• Common (1% to 10%): Fever^[Ref]

Psychiatric

• Common (1% to 10%): Anxiety, fatigue^[Ref]

Respiratory

• Common (1% to 10%): Nasopharyngitis^[Ref]

Further information

Daybue side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer