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DaunoXome Side Effects

Generic name: daunorubicin liposomal

Note: This document contains side effect information about daunorubicin liposomal. Some of the dosage forms listed on this page may not apply to the brand name DaunoXome.

Applies to daunorubicin liposomal: intravenous dispersion

Hematologic

Very common (10% or more): Bone marrow suppression, bone marrow failure, agranulocytosis, neutropenia, febrile neutropenia, leucopenia, pancytopenia, thrombocytopenia, anemia, hemorrhage[Ref]

Cardiovascular

Common (1% to 10%): Decreased left ventricular ejection fraction

Uncommon (0.1% to 1%): Congestive heart failure, cardiomyopathy

Rare (less than 0.1%): Atrial fibrillation, myocardial infarction

Frequency not reported: Shock[Ref]

Dermatologic

Very common (10% or more): Alopecia

Rare (less than 0.1%): Palmar-plantar erythrodysesthesia syndrome[Ref]

Gastrointestinal

Very common (10% or more): Stomatitis, mucous ulcerations, nausea, vomiting, diarrhea, abdominal pain[Ref]

Local

Very common (10% or more): Infusion-associated reactions (e.g., back pain, flushing, chest tightness, dyspnea, allergic reaction), extravasation at the injection site (erythema, pain, swelling)[Ref]

Hepatic

Frequency not reported: Transient elevations in serum bilirubin, transient elevations in aspartate aminotransferase (AST), transient elevations in alkaline phosphatase (ALP), hepatitis, hepatic failure[Ref]

Other

Very common (10% or more): Asthenia, fatigue, fever, chills[Ref]

Immunologic

Very common (10% or more): infections

Uncommon (0.1% to 1%): Sepsis, septic shock[Ref]

Metabolic

Common (1% to 10%): Dehydration[Ref]

Genitourinary

Frequency not reported: Red discoloration of urine, amenorrhea, azoospermia[Ref]

Hypersensitivity

Very common (10% or more): Allergic reaction

Rare (less than 0.1%): Anaphylactic reaction[Ref]

Psychiatric

Common (1% to 10%): Depression[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Medically reviewed by Drugs.com. Last updated on Oct 23, 2020.

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Some side effects may not be reported. You may report them to the FDA.