Generic Name: Daunorubicin (Liposomal) (daw noe ROO bi sin lye po SO mal)
Brand Name: DaunoXome
- This medicine may cause very bad heart problems like heart failure. This can happen during care or months to years after you get DaunoXome (daunorubicin (liposomal)). Sometimes, these heart problems will not go away or may be deadly. The chance of heart problems may be raised if you are using other drugs that may cause heart problems or if you have ever had heart problems or radiation to the chest area, or if you have ever had this medicine or other drugs like this one. Ask your doctor if you are not sure if any drugs you take may cause heart problems. Your chance of heart problems depends on your dose of DaunoXome and your health problem. Heart problems may happen even if you do not have any risk factors. In children, the chance of heart problems later in life is raised. Call your doctor right away if you have cough, fast or slow heartbeat, a heartbeat that does not feel normal, swelling in the arms or legs, shortness of breath, sudden weight gain, or feeling very tired or weak.
- This medicine may lower the ability of your bone marrow to make blood cells that your body needs. This can lead to needing a blood transfusion and very bad and sometimes deadly bleeding problems or infections. Tell your doctor right away if you have signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if you feel very tired or weak.
- You will be watched closely by your doctor.
- If you have liver disease you may need a lower dose. Talk with your doctor.
- Some people have had certain side effects like back pain, flushing, and tightness during the infusion. Tell your doctor if you have any of these side effects.
Uses of DaunoXome:
- It is used to treat advanced HIV-associated Kaposi's sarcoma.
What do I need to tell my doctor BEFORE I take DaunoXome?
- If you have an allergy to daunorubicin or any other part of this medicine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take DaunoXome with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take DaunoXome?
- Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- If you have had daunorubicin, doxorubicin, epirubicin, idarubicin, or mitoxantrone before, talk with your doctor.
- To help with mouth sores, use a soft toothbrush or cotton swabs and rinse the mouth. Do not use mouth rinses that have alcohol in them.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need to have heart function tests while taking DaunoXome. Talk with the doctor.
- Talk with your doctor before getting any vaccines. Use with this medicine may either raise the chance of an infection or make the vaccine not work as well.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking DaunoXome.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (DaunoXome) best taken?
Use DaunoXome as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Chest pain or pressure or passing out.
- A burning, numbness, or tingling feeling that is not normal.
- Very upset stomach or throwing up.
- A big weight loss.
- Very loose stools (diarrhea).
- Any unexplained bruising or bleeding.
- Feeling very tired or weak.
- Change in eyesight.
- Low mood (depression).
- This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
What are some other side effects of DaunoXome?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
- Color of urine is orange or red for 1 to 2 days after getting this medicine.
- Upset stomach or throwing up.
- Belly pain.
- Not hungry.
- Loose stools (diarrhea).
- Hair loss.
- Back pain.
- Mouth and lip irritation.
- Runny nose.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out DaunoXome?
- If you need to store DaunoXome at home, talk with your doctor, nurse, or pharmacist about how to store it.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take DaunoXome (daunorubicin (liposomal)) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to DaunoXome. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: September 6, 2017
More about DaunoXome (daunorubicin liposomal)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
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- Drug class: antibiotics/antineoplastics