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Daunorubicin liposomal Side Effects

Applies to daunorubicin liposomal: intravenous dispersion

Hematologic

Very common (10% or more): Bone marrow suppression, bone marrow failure, agranulocytosis, neutropenia, febrile neutropenia, leucopenia, pancytopenia, thrombocytopenia, anemia, hemorrhage[Ref]

Cardiovascular

Common (1% to 10%): Decreased left ventricular ejection fraction

Uncommon (0.1% to 1%): Congestive heart failure, cardiomyopathy

Rare (less than 0.1%): Atrial fibrillation, myocardial infarction

Frequency not reported: Shock[Ref]

Dermatologic

Very common (10% or more): Alopecia

Rare (less than 0.1%): Palmar-plantar erythrodysesthesia syndrome[Ref]

Gastrointestinal

Very common (10% or more): Stomatitis, mucous ulcerations, nausea, vomiting, diarrhea, abdominal pain[Ref]

Local

Very common (10% or more): Infusion-associated reactions (e.g., back pain, flushing, chest tightness, dyspnea, allergic reaction), extravasation at the injection site (erythema, pain, swelling)[Ref]

Hepatic

Frequency not reported: Transient elevations in serum bilirubin, transient elevations in aspartate aminotransferase (AST), transient elevations in alkaline phosphatase (ALP), hepatitis, hepatic failure[Ref]

Other

Very common (10% or more): Asthenia, fatigue, fever, chills[Ref]

Immunologic

Very common (10% or more): infections

Uncommon (0.1% to 1%): Sepsis, septic shock[Ref]

Metabolic

Common (1% to 10%): Dehydration[Ref]

Genitourinary

Frequency not reported: Red discoloration of urine, amenorrhea, azoospermia[Ref]

Hypersensitivity

Very common (10% or more): Allergic reaction

Rare (less than 0.1%): Anaphylactic reaction[Ref]

Psychiatric

Common (1% to 10%): Depression[Ref]

Medically reviewed by Drugs.com. Last updated on Jan 31, 2021.

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References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.