Ciprofloxacin Otic Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 16, 2024.

Applies to ciprofloxacin otic: otic solution.

Other dosage forms:

• intratympanic suspension

Serious side effects of ciprofloxacin otic

Along with its needed effects, ciprofloxacin otic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ciprofloxacin otic:

Less common

• burning, itching, redness, skin rash, swelling, or soreness at the application site
• changes in hearing
• ear drainage
• earache or pain in the ear
• fever

Other side effects of ciprofloxacin otic

Some side effects of ciprofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• headache

For healthcare professionals

Applies to ciprofloxacin otic: otic solution, otic suspension.

General

The most commonly reported side effects included application site pain, ear pruritus, and headache.^[Ref]

Other

• Common (1% to 10%): Ear pruritus, ear pain, ear discomfort/stinging, otitis media, ear infection (fungal; otomycosis)/fungal ear superinfection
• Postmarketing reports: Crying, ear congestion, otorrhea, pyrexia^[Ref]

Nervous system

• Common (1% to 10%): Headache/cephalea, dizziness, vertigo, dysgeusia/bitter taste
• Uncommon (0.1% to 1%): Tinnitus^[Ref]

Psychiatric

• Common (1% to 10%): Irritability^[Ref]

Respiratory

• Common (1% to 10%): Nasopharyngitis, rhinorrhea^[Ref]

Local

• Common (1% to 10%): Mild local intolerance, application site pain^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Dermatitis

Locally-applied fluoroquinolones:

• Very rare (less than 0.01%): Toxic epidermolysis, exfoliative dermatitis, generalized rash, Stevens-Johnson syndrome, urticaria

Hypersensitivity

• Frequency not reported: Allergic reaction

Systemic quinolone therapy:

• Frequency not reported: Serious and sometimes fatal hypersensitivity (anaphylactic) reactions (some accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal/facial edema, dyspnea, urticaria, itching)

Musculoskeletal

Systemic fluoroquinolones:

• Frequency not reported: Tendon rupture (e.g., shoulder, hand, Achilles)

Further information

Ciprofloxacin otic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer