Ciprofloxacin Otic Dosage

Usual Adult Dose for Acute Otitis Externa

Usual dose: Instill 1 single-use container (approximately 0.5 mg in 0.25 mL) into the affected ear(s) 2 times a day
Duration of therapy: 7 days

Comments:
-Patients should lie with the affected ear upward before administration. Once instilled, the patient should remain in this position for at least 1 minute.
-If both ears are affected, this procedure should be repeated for the opposite ear.

Use: Treatment of acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus

Usual Pediatric Dose for Acute Otitis Externa

1 year and older:
-Usual dose: Instill 1 single-use container (approximately 0.5 mg in 0.25 mL) into the affected ear(s) 2 times a day
-Duration of therapy: 7 days

Comments:
-Patients should lie with the affected ear upward before administration. Once instilled, the patient should remain in this position for at least 1 minute.
-If both ears are affected, this procedure should be repeated for the opposite ear.

Use: Treatment of acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus

Usual Pediatric Dose for Otitis Media

6 months and older:
-Usual dose: After suctioning of middle ear effusion, administer 6 mg intratympanically into the affected ear(s)

Comments:
-The 6% suspension thickens when warmed; if the suspension becomes thick during preparation, the vial should be cooled/refrigerated.
-Different syringes should be used to administer the dose into each ear.

Use: Treatment of patients with bilateral otitis media with effusion who are undergoing tympanostomy tube placement

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy of the intratympanic membrane suspension have not been established in patients younger than 6 months, and the safety and efficacy of the otic solution have not been established in patients younger than 1 year.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Patients should shake the otic solution well before use.
-The otic solution should be warmed in their hands for 1 to 2 minutes prior to administration to avoid dizziness associated with instillation of a cold solution into the ear canal.
-Otic suspension: See manufacturer product information.

Storage requirements:
-This drug should be protected from light when not in use.
-The 6% suspension may be prepared and held in syringes for less than 3 hours. Filled syringes should be kept on their side. If this drug is not administered in 3 hours, the syringes must be discarded.

Reconstitution/preparation techniques:
-See manufacturer product information.

General:
-Limitations of use: This drug is indicated for otic use only. It is not indicated for ophthalmic use or injection.

Patient advice:
-Tell patients that this drug is for otic use only.
-Patients should be instructed to wash their hands before and after applying this drug. Patients should be told to avoid touching the dropper tip to the ear, fingers, or other sources.
-Caution patients to warm the vial in the hands for 1 to 2 minutes to prevent dizziness during administration.
-Patients should be encouraged to avoid missing doses and complete the entire course of therapy.
-Patients should be advised to immediately report any signs/symptoms of hypersensitivity reactions.