Calcijex Side Effects
Generic Name: calcitriol
Note: This page contains information about the side effects of calcitriol. Some of the dosage forms included on this document may not apply to the brand name Calcijex.
For the Consumer
Applies to calcitriol: oral capsules, oral solution, parenteral injection
Side effects include:
Excessive vitamin D intake (early manifestations): weakness, headache, somnolence, nausea, dry mouth, constipation, muscle or bone pain, metallic taste.
Excessive vitamin D intake (late manifestations): polyuria, polydipsia, anorexia, weight loss, nocturia, calcific conjunctivitis, pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated AST, elevated ALT, ectopic calcification, nephrocalcinosis, hypertension, cardiac arrhythmias, dystrophy, sensory disturbances, dehydration, apathy, arrested growth, urinary tract infections.
For Healthcare Professionals
Applies to calcitriol: injectable solution, oral capsule, oral liquid
Early signs of excessive vitamin D intake include weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste, anorexia, abdominal pain, or stomach ache. Late signs include polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis (calcific), pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated AST and ALT, ectopic calcification, nephrocalcinosis, hypertension, cardiac arrhythmias, dystrophy, sensory disturbances, dehydration, apathy, arrested growth, urinary tract infections, and rarely, overt psychosis.[Ref]
Adverse events were similar to those of excessive vitamin D intake, hypercalcemia syndrome or calcium intoxication.[Ref]
Very common (10% or more): Hypercalcemia
Uncommon (0.1% to 1%): Decreased appetite
Frequency not reported: Polydipsia, dehydration, weight loss, thirst, hyperphosphatemia, anorexia, hypercholesterolemia[Ref]
Common (1% to 10%): Hypercalciuria, urinary tract infection
Frequency not reported: Polyuria, nocturia, albuminuria[Ref]
Common (1% to 10%): Headache
Frequency not reported: Sensory disturbance, somnolence, metallic taste
Postmarketing reports: Seizure[Ref]
Frequency not reported: Allergic reaction, hypersensitivity (including rash, erythema, pruritus, and urticaria)
Postmarketing reports: Anaphylaxis[Ref]
Common (1% to 10%): Abdominal pain, nausea
Uncommon (0.1% to 1%): Vomiting
Frequency not reported: Constipation, abdominal pain upper, paralytic ileus, dry mouth, pancreatitis, epigastric discomfort, diarrhea[Ref]
Common (1% to 10%): Rash
Frequency not reported: Urticaria, erythema, pruritus, erythema multiforme[Ref]
Frequency not reported: Cardiac arrhythmias, cardiac arrest, hypertension[Ref]
Frequency not reported: Elevated AST, elevated ALT[Ref]
Frequency not reported: Calcinosis, pyrexia, weakness, hyperthermia, ectopic calcification, dystrophy
Postmarketing reports: Chest pain[Ref]
Uncommon (0.1% to 1%): Blood creatinine increased
Frequency not reported: Elevated BUN, nephrocalcinosis, impairment of renal function[Ref]
Frequency not reported: Muscular weakness, growth retardation, muscle pain, bone pain[Ref]
Frequency not reported: Apathy, psychiatric disturbances, decreased libido, overt psychosis[Ref]
Frequency not reported: Pain on injection
Postmarketing reports: Bleeding at the venipuncture site[Ref]
Postmarketing reports: Hemolysis[Ref]
Postmarketing reports: Brown tumor, non-malignant tumor on the ribs[Ref]
Frequency not reported: Conjunctivitis (calcific), photophobia[Ref]
Frequency not reported: Rhinorrhea[Ref]
1. "Product Information. Calcijex (calcitriol)." Abbott Pharmaceutical, Abbott Park, IL.
2. "Product Information. Rocaltrol (calcitriol)." Roche Laboratories, Nutley, NJ.
3. Cerner Multum, Inc. "Australian Product Information." O 0
4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Not all side effects for Calcijex may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Calcijex (calcitriol)
- Side Effects
- During Pregnancy or Breastfeeding
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- Drug class: vitamins
Other brands: Rocaltrol
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