Byooviz Side Effects
Generic name: ranibizumab ophthalmic
Medically reviewed by Drugs.com. Last updated on Dec 2, 2023.
Note: This document contains side effect information about ranibizumab ophthalmic. Some dosage forms listed on this page may not apply to the brand name Byooviz.
Applies to ranibizumab ophthalmic: intraocular solution. Other dosage forms:
Serious side effects of Byooviz
Along with its needed effects, ranibizumab ophthalmic (the active ingredient contained in Byooviz) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ranibizumab ophthalmic:
More common
- Blindness
- bloody eye
- bloody urine
- blurred vision
- body aches or pain
- burning, numbness, tingling, or painful sensations
- change or loss of vision
- chills
- cough
- decreased amount of urine
- diarrhea
- disturbed color perception
- ear congestion
- eye pain, irritation
- fever
- general feeling of discomfort or illness
- halos around lights
- headache
- increased blood pressure
- increased thirst
- joint pain
- loss of appetite
- loss of voice
- lower back or side pain
- muscle aches and pains
- nausea
- night blindness
- overbright appearance of lights
- pain or tenderness around eyes and cheekbones
- pale skin
- redness of the eye
- seeing floating dark spots or material before the eyes
- seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
- shivering
- sore throat
- stuffy or runny nose
- sweating
- swelling of the face, fingers, hands, ankles, feet, or lower legs
- tearing of the eyes
- trouble breathing
- trouble sleeping
- tunnel vision
- unsteadiness or awkwardness
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting
- weakness in the arms, hands, legs, or feet
- weight gain
Less common
- Chest tightness
- cough producing mucus
- difficulty in moving
- dizziness
- fainting
- fast or irregular heartbeat
- joint pain
- muscle stiffness
- redness, swelling, or itching of the eyelid
- redness of the white part of the eyes or inside of the eyelids
- sensitivity of the eye to light
Incidence not known
- Chest pain or discomfort
- confusion
- difficulty in speaking
- inability to move the arms, legs, or facial muscles
- inability to speak
- pain or discomfort in the arms, jaw, back or neck
- slow speech
Other side effects of Byooviz
Some side effects of ranibizumab ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Constipation
- heartburn
Less common
- Slow wound healing
For Healthcare Professionals
Applies to ranibizumab ophthalmic: intravitreal solution.
Ocular
-Very common (10% or more): Conjunctival hemorrhage (up to 74%), eye pain (up to 35%), vitreous floaters (up to 27%), increased intraocular pressure (up to 24%), vitreous detachment (up to 21%), intraocular inflammation (up to 18%), vision disturbance/blurred vision (up to 18%), cataract (up to 17%), foreign body sensation in eyes (up to 16%), eye irritation (up to 15%), increased lacrimation (up to 14%), blepharitis (up to 12%), dry eye (up to 12%), eye pruritus (up to 12%), ocular hyperemia (up to 11%), maculopathy (up to 11%), retinal disorder (10%), vitreitis, retinal hemorrhage
-Common (1% to 10%): Retinal degeneration, retinal detachment, retinal tear, retinal pigment epithelium detachment, retinal pigment epithelium tear, reduced visual acuity, vitreous hemorrhage, vitreous disorder, uveitis, iritis, iridocyclitis, subcapsular cataract, punctuate keratitis, corneal abrasion, anterior chamber flare, eye hemorrhage, conjunctivitis, allergic conjunctivitis, eye discharge, photopsia, photophobia, ocular discomfort, eyelid edema, eyelid pain, conjunctival hyperemia, posterior capsule opacification, endophthalmitis, injection site hemorrhage
-Uncommon (0.1% to 1%): Blindness, endophthalmitis, hypopyon, hyphema, keratopathy, iris adhesion, corneal deposits, corneal edema, corneal striae, injection site pain, injection site irritation, abnormal sensation in eye, eyelid irritation[Ref]
Respiratory
Very common (10% or more): Nasopharyngitis (up to 16%), bronchitis (up to 11%)
Common (1% to 10%): Cough, upper respiratory tract infection, sinusitis, chronic obstructive pulmonary disease[Ref]
Nervous system
Very common (10% or more): Headache (up to 12%)
Common (1% to 10%): Peripheral neuropathy, stroke[Ref]
Hematologic
Very common (10% or more): Anemia (up to 11%)[Ref]
Musculoskeletal
Very common (10% or more): Arthralgia (up to 11%)[Ref]
Cardiovascular
Very common (10% or more): Arterial thromboembolic events (up to 10.8%)
Common (1% to 10%): Peripheral edema, atrial fibrillation[Ref]
Gastrointestinal
Very common (10% or more): Nausea (up to 10%)
Common (1% to 10%): Constipation, gastroesophageal reflux disease[Ref]
Genitourinary
Common (1% to 10%): Urinary tract infection[Ref]
Hypersensitivity
Common (1% to 10%): Hypersensitivity reactions[Ref]
Immunologic
Common (1% to 10%): Immunoreactivity, seasonal allergy, allergic reactions (rash, urticaria, pruritus, erythema)[Ref]
Metabolic
Common (1% to 10%): Hypercholesterolemia[Ref]
Other
Common (1% to 10%): Influenza, would healing complications, fatal events
Frequency not reported: Non-ocular hemorrhage[Ref]
Psychiatric
Common (1% to 10%): Anxiety[Ref]
Renal
Common (1% to 10%): Renal failure, chronic renal failure[Ref]
Frequently asked questions
More about Byooviz (ranibizumab ophthalmic)
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- Drug class: anti-angiogenic ophthalmic agents
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References
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
2. Product Information. Lucentis (ranibizumab ophthalmic). Genentech. 2006.
3. Cerner Multum, Inc. Australian Product Information.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.