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Bepreve Side Effects

Generic Name: bepotastine ophthalmic

Note: This page contains information about the side effects of bepotastine ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Bepreve.

For the Consumer

Applies to bepotastine ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by bepotastine ophthalmic (the active ingredient contained in Bepreve). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking bepotastine ophthalmic:

Less common:
  • Red, sore eyes
Incidence not known:
  • Body rash
  • itching
  • swelling of the lips, tongue, or throat

Minor Side Effects

Some of the side effects that can occur with bepotastine ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Mild taste in your mouth
Less common:
  • Fever
  • headache
  • muscle aches
  • sore throat
  • stuffy or runny nose
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to bepotastine ophthalmic: ophthalmic solution


The most common side effect reported was a mild taste following instillation.


Common (1% to 10%): Eye irritation[Ref]

Nervous system

Very common (10% or more): Taste abnormality (25%)
Common (1% to 10%): Headache[Ref]


Common (1% to 10%): Nasopharyngitis[Ref]


Postmarketing reports: Itching, body rash, swelling of lips, tongue and/or throat


1. "Product Information. Bepreve (bepotastine ophthalmic)." ISTA Pharmaceuticals, Irvine, CA.

Not all side effects for Bepreve may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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