Benzoyl Peroxide / Sulfur Topical Side Effects
Medically reviewed by Drugs.com. Last updated on Apr 14, 2024.
Applies to benzoyl peroxide/sulfur topical: topical gel, topical lotion.
Important warnings
This medicine can cause some serious health issues
Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Stop using the medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.
Do not use benzoyl peroxide and sulfur topical while you are also using tretinoin (Altinac, Avita, Renova, Retin-A, Tretin-X).
Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.
Stop using this medicine and Get emergency medical help if you have any of these signs of an allergic reaction while taking benzoyl peroxide / sulfur topical: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.
Stop using the medicine if it causes severe burning or excessive dryness or irritation.
Common side effects may include:
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mild burning or stinging after applying the medicine; or
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redness, dryness, or peeling of treated skin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
See also:
For healthcare professionals
Applies to benzoyl peroxide / sulfur topical: topical gel, topical lotion.
Dermatologic adverse events
Dermatologic side effects have most frequently included excessive erythema and peeling (5%).[Ref]
Excessive erythema and peeling occur most often during the initial phase of drug use and may be controlled by reducing the frequency of application.[Ref]
Hypersensitivity
Hypersensitivity reactions in the form of contact sensitization have been reported and are expected to occur in 1% to 2.5% of patients.[Ref]
References
1. "Product Information. Sulfoxyl Regular (benzoyl peroxide-sulfur topical)." Stiefel Laboratories Inc
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Further information
Benzoyl peroxide/sulfur topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.