Bafiertam Side Effects

Generic name: monomethyl fumarate

Medically reviewed by Drugs.com. Last updated on Mar 30, 2025.

Note: This document provides detailed information about Bafiertam Side Effects associated with monomethyl fumarate. Some dosage forms listed on this page may not apply specifically to the brand name Bafiertam.

Applies to monomethyl fumarate: oral capsule delayed release.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests will be needed 6 months after starting treatment, then every 6 to 12 months after, to check for any unwanted effects. Urine tests may also be needed.

Symptoms of your MS may return and become worse after stopping treatment with this medicine. Do not stop using this medicine without checking first with your doctor.

Do not use this medicine together with dimethyl fumarate (Tecfidera®) or diroximel fumarate (Vumerity®). Using these medicines together may increase your risk for more serious side effects.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema. These can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals after using this medicine.

This medicine may increase your risk of developing a serious and rare brain infection called progressive multifocal leukoencephalopathy (PML). Check with your doctor right away if you have vision changes, loss of coordination, clumsiness, memory loss, difficulty speaking or understanding what others say, or weak legs.

This medicine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection (including herpes). If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever, chills, cough, hoarseness, lower back or side pain, or painful or difficult urination.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

Common side effects of Bafiertam

Some side effects of monomethyl fumarate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Bafiertam

Along with its needed effects, monomethyl fumarate (the active ingredient contained in Bafiertam) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking monomethyl fumarate:

For healthcare professionals

Applies to monomethyl fumarate: oral delayed release capsule.

Hematologic adverse events

• Common (1% to 10%): Lymphopenia^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis, angioedema^[Ref]

Immunologic

• Frequency not reported: Herpes zoster, disseminated herpes zoster, herpes zoster ophthalmicus, herpes zoster meningoencephalitis, herpes zoster meningomyelitis, herpes simplex virus, West Nile virus, cytomegalovirus, Candida, Aspergillus, Nocardia, Listeria monocytogenes, Mycobacterium tuberculosis)^[Ref]

Genitourinary

• Common (1% to 10%): Albumin urine present^[Ref]

Hepatic

• Common (1% to 10%): Aspartate aminotransferase increased
• Frequency not reported: Liver injury^[Ref]

Nervous system

• Frequency not reported: Progressive Multifocal Leukoencephalopathy (PML)^[Ref]

Cardiovascular

• Very common (10% or more): Flushing (40%)^[Ref]

Dermatologic

• Common (1% to 10%): Pruritus, rash, erythema^[Ref]

Gastrointestinal

• Very common (10% or more): Abdominal pain (18%), diarrhea (14%), nausea (12%)
• Common (1% to 10%): Vomiting, dyspepsia^[Ref]

See also:

Frequently asked questions

• What are the new drugs used for multiple sclerosis (MS)?

Further information

Bafiertam side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer