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Pantothenic Acid


(pan toe THEN ik AS id)

Index Terms

  • Calcium Pantothenate
  • Vitamin B5

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Capsule, Oral:

Panto-250: 250 mg

Tablet, Oral:

Generic: 100 mg, 200 mg, 500 mg

Tablet, Oral [preservative free]:

Generic: 500 mg

Brand Names: U.S.

  • Panto-250 [OTC]

Pharmacologic Category

  • Vitamin, Water Soluble


Pantothenic acid is required for the synthesis and maintenance of coenzyme A.


Absorbed in the intestine


Hydrolyzed in the intestine to coenzyme A



Use: Labeled Indications

Dietary supplement

Dosing: Adult

Adequate intake (AI) (IOM, 1998): Oral: 5 mg/day

Pregnancy: 6 mg/day

Lactation: 7 mg/day

Dosing: Geriatric

Refer to adult dosing.

Dosing: Pediatric

Adequate intake (AI) (IOM, 1998): Oral:

1-6 months: 1.7 mg/day

7-12 months: 1.8 mg/day

1-3 years: 2 mg/day

4-8 years: 3 mg/day

9-13 years: 4 mg/day

≥14 years: Refer to adult dosing.

Drug Interactions

There are no known significant interactions.

Pregnancy Considerations

Water soluble vitamins cross the placenta (IOM, 1998).

Patient Education

• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)

• Have patient report immediately to prescriber severe nausea, severe vomiting, or severe diarrhea (HCAHPS).

• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.

Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating, and advising patients.