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REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots

Medically reviewed by Drugs.com. Last updated on May 24, 2021.

Dosage form: kit
Ingredients: Hydroquinone 2g in 100mL; Avobenzone 3.0g in 100mL, Homosalate 10g in 100mL, Octisalate 5g in 100mL, Octocrylene 2.6g in 100mL
Labeler: Rodan & Fields, LLC.
NDC Code: 14222-5030

Broad Spectrum SPF 50+ Sunscreen

50 mL/1.7 Fl. Oz. U.S.

Drug Facts

Active Ingredients

Avobenzone 3%

Homosalate 10%

Octisalate 5%

Octocrylene 2.6%

Purpose

Sunscreen

Uses
  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun

Warnings

For external use only

Do not use on damaged or broken skin

When using this product keep out of eyes. Rinse with water to remove.

Stop use and ask doctor if rash occurs

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions
  • Apply liberally 15 minutes before sun exposure
    • Reapply at least every 2 hours
    • Use a water-resistant sunscreen if swimming or sweating
  • Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including:
    • limit time in the sun, especially from 10 a.m.-2 p.m.
    • wear long-sleeve shirts, pants, hats and sunglasses
  • Children under 6 months: Ask a doctor

Other Information
  • Protect this product from excessive heat and direct sun.

Inactive Ingredients

Water/Aqua/Eau, Caprylyl Methicone, Dipropylene Glycol, Dicaprylyl Carbonate, PEG/PPG-17/6 Copolymer, Alcohol Denat., Methyl Glucose Sesquistearate, Potassium Cetyl Phosphate, Dipotassium Glycyrrhizate, Adenosine, Tocopheryl Acetate, Euterpe Oleracea Fruit Extract, Morus Alba Root Extract, Portulaca Oleracea Extract, Camellia Oleifera Leaf Extract, Dunaliella Salina Extract, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyacrylate-15, Cetyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Hydrogenated Palm Glycerides, Fragrance/Parfum, Isohexadecane, Panthenol, Butylene Glycol, PEG-10 Dimethicone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyacrylate-17, Polysorbate 80, Polydecene, C11-15 Pareth-40, C11-15 Pareth-7, Sorbitan Oleate, Disodium Lauryl Sulfosuccinate, Sodium Laureth-12 Sulfate, Potassium Hydroxide, Disodium EDTA, Tetrasodium EDTA, Phenoxyethanol, Caprylyl Glycol, Citral, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Limonene, Linalool.

Skin Lightening Treatment

50 mL/1.7 Fl. Oz. U.S.

Drug Facts

Active Ingredients

Hydroquinone 2%

Purpose

Skin lightener

Uses

For the gradual fading of dark areas such as freckles, age and liver spots, or pigment in the skin that may occur in pregnancy or from the use of oral contraceptives.

Warnings

For external use only

When using this product
  • Avoid contact with eyes

Stop use and ask doctor if
  • Condition worsens
  • Symptoms last more than 7 days or clear up and occur again within a few days

Do not use on
  • Deep or puncture wounds
  • Animal bites
  • Serious burns

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Apply a thin, even layer over the entire face, avoiding the eye area. Do not rinse off. Use twice daily. Apply as needed.

  • Adults: apply a small amount as a thin layer on affected area once or twice daily, or use as directed by a doctor. If no improvement is seen after three months of treatment, use of this product should be discontinued. Lightening effect of this product may not be noticeable when used on very dark skin.
  • Sun exposure should be limited by using a sunscreen agent, a sun blocking agent,or protective clothing to cover bleached skin when using and after using the product in order to prevent darkening from reoccurring.
  • Children under 12 years of age: do not use unless directed by a doctor.

Inactive Ingredients

Water/Aqua/Eau, Ethoxydiglycol, Cetearyl Alcohol, PPG-12/SMDI Copolymer, Diethylhexyl Sebacate, Polyacrylamide, Ceteareth-20, Glycerin, C13-14 Isoparaffin, Dimethicone, Fragrance/Parfum, Retinol, Ascorbyl Palmitate, Magnesium Ascorbyl Phosphate, Lactic Acid, Arctostaphylos Uva Ursi Leaf Extract, Sodium C14-16 Olefin Sulfonate, Sodium Metabisulfite, Laureth-7, Glyceryl Stearate, PEG-100 Stearate, Tocopheryl Acetate, Citric Acid, Glycine Soja (Soybean) Oil, Propylene Glycol, Disodium EDTA, BHT, Methylparaben, Propylparaben, Benzoic Acid, Sorbic Acid, Chlorphenesin, Imidazolidinyl Urea, Phenoxyethanol, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Limonene, Linalool, Yellow 5 (CI 19140), Yellow 6 (CI 15985).

Skin Lightening Toner

125 mL/4.2 Fl. Oz. U.S.

Drug Facts

Active Ingredients

Hydroquinone 2%

Purpose

Skin lightener

Uses

For the gradual fading of dark areas such as freckles, age and liver spots, or pigment in the skin that may occur in pregnancy or from the use of oral contraceptives.

Warnings

For external use only

When using this product
  • Avoid contact with eyes

Stop use and ask doctor if
  • Condition worsens
  • Symptoms last more than 7 days or clear up and occur again within a few days

Do not use on
  • Deep or puncture wounds
  • Animal bites
  • Serious burns

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Apply a thin, even layer over the entire face, avoiding the eye area. Do not rinse off. Use twice daily. Apply as needed.

  • Adults: apply a small amount as a thin layer on affected area once or twice daily, or use as directed by a doctor. If no improvement is seen after three months of treatment, use of this product should be discontinued. Lightening effect of this product may not be noticeable when used on very dark skin.
  • Sun exposure should be limited by using a sunscreen agent, a sun blocking agent,or protective clothing to cover bleached skin when using and after using the product in order to prevent darkening from reoccurring.
  • Children under 12 years of age: do not use unless directed by a doctor.

Inactive Ingredients

Water/Aqua/Eau, Ethoxydiglycol, Hamamelis Virginiana (Witch Hazel) Water, Methylpropanediol, Alcohol, Polysorbate 20, Kojic Acid, Salicylic Acid, Magnesium Ascorbyl Phosphate, Arctostaphylos Uva Ursi Leaf Extract, Arnica Montana Flower Extract, Citrus Limon (Lemon) Peel Extract, Foeniculum Vulgare (Fennel) Fruit Extract, Sodium Sulfite, Fragrance/Parfum, PEG-12 Dimethicone, Zinc Phenolsulfonate, Citric Acid, Sodium Metabisulfite, Sodium Hydroxide, Propylene Glycol, Phenoxyethanol, Chlorphenesin, DMDM Hydantoin, Benzoic Acid, Sorbic Acid, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Limonene, Linalool, Yellow 5 (CI 19140), Yellow 6 (CI 15985).

Deep Exfoliating Wash

125 mL/4.2 Fl. Oz. U.S.

Product Details

Directions

Wet skin with lukewarm water. Using fingertips, gently and evenly massage a thin, even layer over the entire face for 30-60 seconds, avoiding contact with eyes. Rinse thoroughly with water and pat dry. Use once every other day for the first week and increase to twice daily as tolerated.

Warnings

For external use only. When using this product keep out of eyes. Rinse with water to remove. If irritation or rash occurs, discontinue use and consult your doctor. Keep out of reach of children. If product is swallowed, seek medical attention.

Ingredients

Water/Aqua/Eau, C12-15 Alkyl Benzoate, Diethylhexyl Sebacate, Polylactic Acid, Cetearyl Alcohol, Jojoba Esters, PEG-40 Stearate, Glyceryl Stearate, Ammonium Laureth Sulfate, Magnesium Aluminum Silicate, Pentylene Glycol, Potassium Cetyl Phosphate, Ceteareth-20, Hydroxyacetophenone, Lactic Acid, Mentha Piperita (Peppermint) Oil, Fragrance/Parfum, Xanthan Gum, Glycolic Acid, Sodium Magnesium Silicate, Propylene Glycol, Citric Acid, Phenoxyethanol, Potassium Sorbate, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Limonene, Linalool, Yellow 5 (CI 19140), Yellow 6 (CI 15985).

Principal Display Panel - Rodan + Fields Reverse Skin Lightening Toner Label

RODAN + FIELDS®
REVERSE

2 Skin Lightening
Toner

Principal Display Panel - Rodan + Fields Reverse Skin Lightening Treatment Label

RODAN + FIELDS®
REVERSE

3 Skin Lightening
Treatment

Principal Display Panel - Rodan + Fields Reverse Broad Spectrum SPF 50+ Sunscreen Label

RODAN + FIELDS®
REVERSE

4 Broad Spectrum
SPF 50+ Sunscreen

Principal Display Panel - Rodan + Fields Reverse Lightening Regimen Carton Label

RODAN + FIELDS®
REVERSE™

Regimen for the Appearance of Stubborn
Dark Marks, Patches and Age Spots

Based on Multi-Med® Therapy, the REVERSE Lightening
Regimen is a complete skincare system that combines
cosmetic and OTC ingredients to gradually lighten stubborn
dark marks, patches and excessive pigmentation. The highly
effective formulas contains 2% Hydroquinone to address
persistent discoloration for a more even, youthful complexion.

This 4-product Regimen was developed by Stanford-trained
dermatologists Dr. Katie Rodan and Dr. Kathy Fields.

RODAN + FIELDS®

LIGHTENING

Deep Exfoliating Wash

125 mL/
4.2 Fl.Oz. U.S.

Skin Lightening Toner

125 mL/
4.2 Fl.Oz. U.S.

Skin Lightening Treatment

50 mL/
1.7 Fl.Oz. U.S.

Broad Spectrum
SPF 50+ Sunscreen

50 mL/
1.7 Fl.Oz. U.S.

REVERSE LIGHTENING REGIMEN FOR THE APPEARANCE OF STUBBORN DARK MARKS, PATCHES AND AGE SPOTS 
hydroquinone, avobenzone, homosalate, octisalate, octocrylene kit
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:14222-5030
Packaging
#Item CodePackage Description
1NDC:14222-5030-11 KIT in 1 CARTON
Quantity of Parts
Part #Package QuantityTotal Product Quantity
Part 11 TUBE 50 mL
Part 21 BOTTLE 125 mL
Part 31 TUBE 50 mL
Part 1 of 3
SKIN LIGHTENING TONER 
hydroquinone lotion
Product Information
Route of AdministrationTOPICALDEA Schedule    
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Hydroquinone (Hydroquinone) Hydroquinone2 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
Water 
Diethylene Glycol Monoethyl Ether 
Hamamelis Virginiana Top Water 
Methylpropanediol 
Alcohol 
Polysorbate 20 
Kojic Acid 
Salicylic Acid 
Magnesium Ascorbyl Phosphate 
Arctostaphylos Uva-Ursi Leaf 
Arnica Montana Flower 
Lemon Peel 
Fennel Seed 
Sodium Sulfite 
PEG-12 Dimethicone 
Zinc Phenolsulfonate 
Citric Acid Monohydrate 
Sodium Metabisulfite 
Sodium Hydroxide 
Propylene Glycol 
Phenoxyethanol 
Chlorphenesin 
DMDM Hydantoin 
Benzoic Acid 
Sorbic Acid 
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde 
Limonene, (+)- 
Linalool, (+/-)- 
FD&C Yellow No. 5 
FD&C Yellow No. 6 
Packaging
#Item CodePackage Description
150 mL in 1 TUBE
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph not finalpart358A06/01/2017
Part 2 of 3
SKIN LIGHTENING TREATMENT 
hydroquinone liquid
Product Information
Route of AdministrationTOPICALDEA Schedule    
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Hydroquinone (Hydroquinone) Hydroquinone2 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
Water 
Diethylene Glycol Monoethyl Ether 
Cetostearyl Alcohol 
PPG-12/SMDI Copolymer 
Diethylhexyl Sebacate 
Polyacrylamide (1500 MW) 
Polyoxyl 20 Cetostearyl Ether 
Glycerin 
C13-14 Isoparaffin 
Dimethicone 
Retinol 
Ascorbyl Palmitate 
Magnesium Ascorbyl Phosphate 
Lactic Acid 
Arctostaphylos Uva-Ursi Leaf 
Sodium C14-16 Olefin Sulfonate 
Sodium Metabisulfite 
Laureth-7 
Glyceryl Monostearate 
PEG-100 Stearate 
.Alpha.-Tocopherol Acetate 
Citric Acid Monohydrate 
Soybean Oil 
Propylene Glycol 
Edetate Disodium Anhydrous 
Butylated Hydroxytoluene 
Methylparaben 
Propylparaben 
Benzoic Acid 
Sorbic Acid 
Chlorphenesin 
Imidurea 
Phenoxyethanol 
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde 
Limonene, (+)- 
Linalool, (+/-)- 
FD&C Yellow No. 5 
FD&C Yellow No. 6 
Packaging
#Item CodePackage Description
1125 mL in 1 BOTTLE
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph not finalpart358A
Part 3 of 3
BROAD SPECTRUM SPF 50 SUNSCREEN 
avobenzone, homosalate, octisalate, octocrylene lotion
Product Information
Route of AdministrationTOPICALDEA Schedule    
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Avobenzone (Avobenzone) Avobenzone3.0 g  in 100 mL
Homosalate (Homosalate) Homosalate10 g  in 100 mL
Octisalate (Octisalate) Octisalate5 g  in 100 mL
Octocrylene (Octocrylene) Octocrylene2.6 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
Water 
Caprylyl Trisiloxane 
Dipropylene Glycol 
Dicaprylyl Carbonate 
PEG/PPG-17/6 Copolymer 
Alcohol 
Methyl Glucose Sesquistearate 
Potassium Cetyl Phosphate 
Glycyrrhizinate Dipotassium 
Adenosine 
.Alpha.-Tocopherol Acetate 
Acai 
Morus Alba Root 
Purslane 
Camellia Oleifera Leaf 
Dunaliella Salina 
Sodium Acrylate/Sodium Acryloyldimethyltaurate Copolymer (4000000 MW) 
Cetyl Alcohol 
Glyceryl Monostearate 
PEG-100 Stearate 
Hydrogenated Palm Glycerides 
Isohexadecane 
Panthenol 
Butylene Glycol 
PEG-10 Dimethicone (600 CST) 
Carbomer Interpolymer Type A (Allyl Sucrose Crosslinked) 
Polysorbate 80 
Hydrogenated Polydecene (550 MW) 
C11-15 Pareth-40 
C11-15 Pareth-7 
Sorbitan Monooleate 
Disodium Lauryl Sulfosuccinate 
Sodium Laureth-12 Sulfate 
Potassium Hydroxide 
Edetate Disodium Anhydrous 
Edetate Sodium 
Phenoxyethanol 
Caprylyl Glycol 
Citral 
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde 
Limonene, (+)- 
Linalool, (+/-)- 
Packaging
#Item CodePackage Description
150 mL in 1 TUBE
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph not finalpart352
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
unapproved drug other06/01/2017
Labeler - Rodan & Fields, LLC. (051659584)

 
Rodan & Fields, LLC.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.