Generic Name: horse chestnut (HORSE CHEST nut)
Brand Name: Venastat
What is Venastat (horse chestnut)?
Horse chestnut is a plant also known as Aescin, Aesculus hippocastanum, Buckeye, Castaño de Indias, Châtaignier de Mer, Châtaignier des Chevaux, Escine, Faux-Châtaignier, Hippocastani, Hippocastanum Vulgare Gaertn, Marron Europeen, Marronnier, Spanish Chestnut, Venostasin Retard, Venostat, White Chestnut, and other names.
Horse chestnut has been used in alternative medicine and is likely effective in treating some symptoms of chronic venous insufficiency (decreased blood flow return from the feet and legs back to the heart). These symptoms include leg pain or tenderness, varicose veins, itching or swelling in the legs, and fluid retention (puffy or swollen ankles or feet).
Other uses not proven with research have included fever, cough, diarrhea, hemorrhoids, enlarged prostate, menstrual cramps, and swelling caused by arthritis, sprains, or bone fractures.
It is not certain whether horse chestnut is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Horse chestnut should not be used in place of medication prescribed for you by your doctor.
Horse chestnut is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Horse chestnut may also be used for purposes not listed in this product guide.
What is the most important information I should know about Venastat (horse chestnut)?
Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before using Venastat (horse chestnut)?
Before using horse chestnut, talk to your healthcare provider. You may not be able to use horse chestnut if you have certain medical conditions, such as:
a bleeding or blood clotting disorder (horse chestnut can thin your blood);
diabetes (horse chestnut may cause low blood sugar);
a stomach or intestinal disorder;
congestive heart disease;
migraine headaches; or
if you are allergic to latex.
It is not known whether horse chestnut will harm an unborn baby. Do not use this product if you are pregnant.
Horse chestnut may pass into breast milk and may harm a nursing baby. Do not use this product if you are breast-feeding a baby.
Do not give any herbal/health supplement to a child without medical advice.
How should I use Venastat (horse chestnut)?
When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.
If you choose to use horse chestnut, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.
The usual dose of horse chestnut in capsule form is 1 capsule every 12 hours before a meal.
Take the capsule with a full glass of water.
Do not crush, chew, break, or open a horse chestnut capsule. Swallow it whole.
It is best to use a horse chestnut product that contains an exact amount of the labeled chemical. Check the label to be sure your product does not contain a toxic substance called "esculin."
It may take up to 4 weeks before your symptoms improve. Call your doctor if your symptoms do not improve, or if they get worse while using horse chestnut.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra horse chestnut to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. The use of raw horse chestnut (seeds, flowers, stems, leaves) can cause fatal poisoning.
Signs of horse chestnut poisoning may include weakness, depressed mood, loss of coordination, dilated pupils, vomiting, diarrhea, little or no urinating, muscle twitching, or loss of movement in any part of the body.
What should I avoid while taking Venastat (horse chestnut)?
Avoid the use of raw horse chestnut seed, bark, flower, or leaves. These items are not safe to take by mouth and may cause fatal side effects.
Avoid using horse chestnut together with other herbal/health supplements that can lower blood sugar, such as alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, Panax ginseng, psyllium, Siberian ginseng, and others.
Avoid using horse chestnut together with herbal/health supplements that can also affect blood-clotting. This includes angelica (dong quai), capsicum, clove, danshen, garlic, ginger, ginkgo, panax ginseng, poplar, red clover, turmeric, and willow.
Venastat (horse chestnut) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although not all side effects are known, horse chestnut is thought to be possibly safe when taken for a short period of time.
Stop using horse chestnut and call your healthcare provider at once if you have:
severe skin redness, swelling, itching, or rash.
Common side effects may include:
headache, dizziness; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Venastat (horse chestnut)?
Do not take horse chestnut without medical advice if you are using any of the following medications:
insulin or oral diabetes medicine;
medicines to prevent blood clots--clopidogrel (Plavix), dalteparin, enoxaparin, heparin, warfarin (Coumadin, Jantoven), and others; or
an NSAID (nonsteroidal anti-inflammatory drug)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with horse chestnut, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this product guide.
Where can I get more information?
- Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02.
Date modified: June 01, 2017
Last reviewed: March 03, 2015