Generic Name: regadenoson (re ga DEN oh son)
Brand Name: Lexiscan
Medically reviewed: September 6, 2017
What is regadenoson?
Regadenoson is a stress agent that works by increasing blood flow in the arteries of the heart.
Regadenoson may also be used for purposes not listed in this medication guide.
You should not receive regadenoson if you have a serious heart condition such as AV block or "sick sinus syndrome" (unless you have a pacemaker).
Before taking this medicine
You should not use this medication if you are allergic to regadenoson, or if you have a serious heart condition such as AV block or "sick sinus syndrome" (unless you have a pacemaker).
To make sure regadenoson is safe for you, tell your doctor if you have ever had:
chest pain or heart problems;
heart disease or high blood pressure;
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether regadenoson passes into breast milk or if it could harm a nursing baby. Do not breast-feed within 10 hours after receiving regadenoson. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
How is regadenoson given?
Regadenoson is injected into a vein through an IV. A healthcare provider will give you this injection.
After regadenoson is injected, you will be given other intravenous (IV) medications that allow blood vessels to be seen more clearly on the radiologic examination.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely during your stress test.
What happens if I miss a dose?
Since regadenoson is given by a healthcare professional in preparation for medical testing, you are not likely to be on a dosing schedule.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving regadenoson?
Avoid drinking coffee or other beverages with caffeine for at least 12 hours before your stress test.
Regadenoson side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregiver right away if you have:
severe dizziness, fast heartbeats, and warmth or a tingly feeling;
weak or shallow breathing;
a light-headed feeling, like you might pass out;
wheezing, chest tightness, trouble breathing;
a severe headache or pounding in your neck or ears;
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; or
signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.
Common side effects may include:
feeling short of breath;
chest pain or discomfort;
flushing (warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.
See also: Side effects (in more detail)
Regadenoson dosing information
Usual Adult Dose for Radionuclide Myocardial Perfusion Study:
0.4 mg rapid IV injection (approximately 10 seconds) into a peripheral vein using a 22 gauge or larger catheter or needle.
Comments: Administer a 5 mL saline flush immediately after injection of this drug. Administer the radionuclide myocardial perfusion imaging agent 10 to 20 seconds after the saline flush. The radionuclide may be injected directly into the same catheter as this drug.
Use: Radionuclide myocardial perfusion imaging (MPI) in patients unable to undergo adequate exercise stress.
What other drugs will affect regadenoson?
Other drugs may interact with regadenoson, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 5.01.
More about regadenoson
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 12 Reviews – Add your own review/rating
- Drug class: cardiac stressing agents
Other brands: Lexiscan