Generic name: tagraxofusp [ tag-RAX-oh-fusp ]
Drug class: Miscellaneous antineoplastics

Medically reviewed by Drugs.com on Jul 22, 2024. Written by Cerner Multum.

What is Elzonris?

Elzonris is used to treat blastic plasmacytoid dendritic cell neoplasm, a rare blood and/or bone marrow cancer.

Elzonris is for use in adults and children at least 2 years old.

Elzonris may also be used for purposes not listed in this medication guide.

Elzonris side effects

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching; mouth sores; sudden warmth or tingly feeling; difficult breathing; swelling of your face, lips, tongue, or throat.

Capillary leak syndrome is a serious side effect of tagraxofusp. Call your doctor right away if you have a stuffy or runny nose followed by:

• tiredness or dizziness;

• thirst;

• decreased urination;

• trouble breathing; and

• sudden swelling or weight gain.

Common side effects of Elzonris may include:

• capillary leak syndrome;

• nausea;

• tiredness;

• swelling in your hands or feet;

• fever; or

• weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Call your doctor right away if you have signs of a serious side effect called capillary leak syndrome: stuffy or runny nose followed by tiredness or dizziness, thirst, decreased urination, trouble breathing, and sudden swelling or weight gain.

Before taking this medicine

You may need to have a negative pregnancy test 1 week before starting this treatment.

Elzonris may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using Elzonris and for at least 1 week after your last dose.

Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

How is Elzonris given?

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Elzonris.

Elzonris is given as an infusion into a vein. A healthcare provider will give you this injection.

You may receive this medicine in a hospital or clinic setting to quickly treat any serious side effects.

You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.

Elzonris is given in a 21-day treatment cycle. You may need to use the medicine only during the first 5 days of each cycle. Your doctor will determine how long to treat you with this medicine.

You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed or permanently discontinued based on the results.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Elzonris.

What happens if I overdose?

Since Elzonris is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Elzonris?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Elzonris?

Other drugs may affect Elzonris, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Elzonris Biosimilars

Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.

Reference products

These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for Elzonris.

Frequently asked questions

• What disease is Elzonris (tagraxofusp-erzs) used to treat?

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2025 Cerner Multum, Inc. Version: 1.02.