Generic Name: edrophonium (ED roe FOE nee um)
Brand Name: Enlon, Reversol, Tensilon
What is edrophonium?
Edrophonium is used as part of a medical test to help diagnose a muscle disorder called myasthenia gravis.
Edrophonium is sometimes used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures.
Edrophonium may also be used for purposes not listed in this medication guide.
What is the most important information I should know about edrophonium?
You should not receive edrophonium if you have a blockage in your intestines, or if you are unable to urinate.
What should I discuss with my health care provider before receiving edrophonium?
You should not receive edrophonium if you are allergic to it, or if you have:
a blockage in your intestines; or
if you are unable to urinate.
To make sure edrophonium is safe for you, tell your doctor if you have:
a heart rhythm disorder; or
if you are allergic to sulfites.
It is not known whether edrophonium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
Do not receive this medication without telling your doctor if you are breast-feeding a baby.
How is edrophonium given?
Edrophonium is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.
When used in testing for myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for certain reactions to this medicine (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.
The test you are receiving may be repeated a second time.
Your specific edrophonium test may be performed in a different manner than described above.
What happens if I miss a dose?
Since edrophonium is given by a healthcare professional, it is not likely that you will miss a dose.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid after receiving edrophonium?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Edrophonium side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have:
slow heartbeats, weak or shallow breathing, feeling like you might pass out;
vision problems, eye redness or watering;
trouble speaking or swallowing;
cough with mucus, wheezing, feeling short of breath;
increased salivation, nausea, vomiting, diarrhea, stomach pain;
muscle weakness, twitching or involuntary movement;
increased sweating, urinating more than usual; or
loss of bowel or bladder control.
Common side effects (some of which can be expected as part of a positive test reaction) may include:
watery eyes, vision problems;
changes in your voice;
mild nausea, vomiting, diarrhea, stomach pain;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect edrophonium?
Other drugs may interact with edrophonium, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about edrophonium
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- Drug class: cholinergic muscle stimulants
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Where can I get more information?
- Your doctor or pharmacist can provide more information about edrophonium.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.
Date modified: November 15, 2017
Last reviewed: June 26, 2014