Generic name: lebrikizumab [ LEB-ri-KIZ-ue-mab ]
Drug class: Interleukin inhibitors

Medically reviewed by Drugs.com on Dec 19, 2024. Written by Cerner Multum.

What is Ebglyss Prefilled Pen?

Ebglyss Prefilled Pen is used alone or with topical medications (for the skin) to treat moderate-to-severe eczema (atopic dermatitis) in adults and children at least 12 years old that weigh at least 88 pounds (40 kg). This medicine is used when other topical treatments did not work or stopped working.

Ebglyss Prefilled Pen may also be used for purposes not listed in this medication guide.

Ebglyss Prefilled Pen side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Ebglyss Prefilled Pen may cause serious side effects. Call your doctor at once if you have:

• eye pain, or changes in your vision such as blurred vision;

• skin rash; or

• stomach cramps.

Common side effects of Ebglyss Prefilled Pen may include:

• pain, bruising, swelling, or irritation where the medicine was injected;

• redness, swelling, itching or inflammation of your eyes or eyelids, or

• skin sores or blisters, itching, tingling, burning pain, rash on your face or torso.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Ebglyss Prefilled Pen if you are allergic to it.

Tell your doctor if you have or have ever had:

• eye problems;

• infection caused by helminthic parasites; or

• if you recently received or are scheduled for a a vaccine.

Make sure you are current on all vaccines before you start using Ebglyss Prefilled Pen.

Do not allow a child to use Ebglyss Prefilled Pen without help from an adult.

While you are using Ebglyss Prefilled Pen, you may also have an increased risk of becoming infected with parasites (helminths). Talk with your doctor about what to look out for and how to treat this condition.

It is not known if Ebglyss Prefilled Pen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, you may be asked to share information to track the effects of lebrikizumab on you and the baby.

Ask a doctor if it is safe to breastfeed while using Ebglyss Prefilled Pen.

How should I use Ebglyss Prefilled Pen?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ebglyss Prefilled Pen is injected under the skin in the stomach, thigh, or upper arm, usually once every 2 to 4 weeks. Your first dose may be given in 2 injections to receive the total dose.

A healthcare provider may teach you or your caregiver how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Prepare an injection only when you are ready to give it. Leave the needle cap on until you are ready to inject your dose. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.

Do not inject within 2 inches of your navel (belly button), or areas where the skin is red, hard, tender, bruised, or with lesions. Do not inject into the same place two times in a row.

Throw away a prefilled syringe or pen after one use, even if there is still medicine left inside. Do not reuse a needle, syringe or pen. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Store this medicine in the original container in the refrigerator. Protect from light and do not freeze or shake it.

Take the medicine out of the refrigerator and let it reach room temperature for 45 minutes before injecting your dose. Do not heat a syringe or pen with hot water, sunlight, or a microwave.

You may store this medicine in the original container at room temperature for up to 7 days. Throw the medicine away if not used within 7 days. Do not put it back into the refrigerator.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then go back to your regular schedule. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Ebglyss Prefilled Pen?

Avoid receiving a "live" vaccine during treatment or right before starting treatment with Ebglyss Prefilled Pen. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Avoid using topical medications unless your doctor tells you to.

What other drugs will affect Ebglyss Prefilled Pen?

Other drugs may affect Ebglyss Prefilled Pen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Biological Products Related to Ebglyss

Find detailed information on biosimilars for this medication.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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