Medically reviewed on March 5, 2018
What is CoQ10?
CoQ10 is a vitamin-like substance that is made naturally in the body. This medicine is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.
CoQ10 is likely effective in alternative medicine as an aid in treating coenzyme Q-10 deficiency, or reducing the symptoms of mitochondrial disorders (conditions that affect energy-production in the cells of the body).
CoQ10 is also possibly effective in preventing migraine headaches, lowering blood pressure, preventing a second heart attack, or slowing the progression of early Parkinson's disease. This medicine is also possibly effective in improving symptoms in people with congestive heart failure, nerve problems caused by diabetes, Huntington's disease, muscular dystrophy, or macular degeneration (age-related vision loss).
CoQ10 has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis (Lou Gehrig's disease). However, research has shown that this medicine may not be effective in treating these conditions.
Research also has shown that CoQ10 is not likely to be effective in increasing athletic performance.
Other uses not proven with research have included treating asthma, COPD, cancer, diabetes, certain heart problems, fibromyalgia, hepatitis C, kidney problems, high blood pressure during pregnancy, muscle problems caused by taking "statin" cholesterol medicine, and other conditions.
CoQ10 is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
CoQ10 may also be used for purposes not listed in this product guide.
Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have ever had:
CoQ10 is considered possibly safe to use during pregnancy. However, do not use this product without medical advice if you are pregnant.
It is not known whether ubiquinone passes into breast milk or if it could harm a nursing baby. Do not use this product without medical advice if you are breast-feeding a baby.
Do not give any herbal/health supplement to a child without a doctor's advice.
How should I take CoQ10?
When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.
If you choose to use CoQ10, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.
Measure liquid CoQ10 carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
To take the disintegrating tablet, use dry hands to remove the tablet from the package, and place it in your mouth. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
Do not use different forms of ubiquinone at the same time without medical advice. Using different formulations together increases the risk of an overdose.
Your blood pressure may need to be checked while you are taking CoQ10.
If you need surgery, stop taking CoQ10 at least 2 weeks ahead of time.
Store CoQ10 at room temperature, away from light, heat, and moisture. Keep the medicine bottle closed when not in use.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking CoQ10?
Avoid using CoQ10 together with other herbal/health supplements that can also lower blood pressure. This includes andrographis, casein peptides, cat's claw, fish oil, L-arginine, lycium, stinging nettle, or theanine.
CoQ10 side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although not all side effects are known, CoQ10 is thought to be likely safe for most adults when used as directed.
Stop using CoQ10 and call your healthcare provider at once if you have:
very low blood pressure--dizziness, severe weakness, feeling like you might pass out.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect CoQ10?
Do not take CoQ10 without medical advice if you are using any of the following medications:
omega-3 fatty acids;
vitamins (especially A, C, E, or K);
blood pressure medicine;
cancer medicine; or
- Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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