How is Vantrela ER formulated to be abuse deterrent?
Vantrela ER (hydrocodone bitartrate) uses Teva's proprietary abuse-deterrent technology based on a multi-layer gel-forming polymer coating that regulates drug release.
What is Vantrela ER?
Vantrela ER (hydrocodone) is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.
Vantrela ER is formulated as extended-release tablets. It is a Schedule II controlled substance with a high potential for abuse and and dependence.
How is Vantrela ER Abuse-Deterrent?
Vantrela ER is formulated with physicochemical properties intended to make the tablet more difficult to manipulate. A multi-layer gel-forming polymer coating regulates drug release.
Vantrela ER resists crushing, breaking, and dissolution using a variety of tools and solvents and still retains some extended-release properties despite manipulation.
Vantrela ER will become viscous when crushed and dissolved in liquid, making injection difficult.
The abuse-deterrent properties of Vantrela ER are expected to reduce, but not totally prevent, oral, intranasal and intravenous abuse of the drug when the tablets are manipulated.
Read next
Which drugs cause opioid-induced constipation?
Any drug that is classified as an "opioid" can cause constipation. Examples of commonly prescribed opioids that may cause this side effect include morphine, tramadol, fentanyl, methadone, hydrocodone, codeine and oxycodone.
Continue reading
What drugs cause pinpoint pupils​?
Pinpoint pupils, medically termed miosis, refer to abnormally small, constricted pupils that do not dilate appropriately in low light. This symptom is a significant clinical clue and can be caused by various drugs and toxins. Some examples include opioids, clonidine, buspirone, and metoclopramide.
Continue reading
Naproxen vs ibuprofen: What's the difference?
Ibuprofen is short acting, while naproxen is long acting and more likely to cause an upset stomach. Naproxen also increases the risk of uncontrolled bleeding in people taking blood thinners by 4-fold, and ibuprofen increases the risk 2-fold. Naproxen and ibuprofen are both NSAIDs so they are similar in many ways, but there are important differences. Continue reading
See also:
Related medical questions
- Oxycodone vs Hydrocodone - How do they compare?
- Which painkiller should you use?
- Norco vs Vicodin - How do they compare?
- Treating Opioid Overdose with Naloxone
- Meloxicam vs Ibuprofen: What's the difference?
- Aleve vs Ibuprofen: What's the difference?
- What is low dose naltrexone (LDN)?
- Can you take ibuprofen on an empty stomach?
- Can you take expired ibuprofen?
- What's the difference between aspirin and ibuprofen?
- Can you overdose on ibuprofen?
- Can you take tramadol with acetaminophen, ibuprofen, or aspirin?
- Does gabapentin help treat nerve pain?
- Can you drink alcohol with ibuprofen?
- Acetaminophen vs paracetamol: What do you need to know?
- How do Celebrex and ibuprofen compare?
- Should I take meloxicam at night or in the morning?
- Can you take Advil & Tylenol together? Safe Dosing Guide
- How much ibuprofen can I take and how often?
- How long can you take Celebrex for?
- Acetaminophen vs Ibuprofen: Which is better?
- What is Metamizole used for?
- Tylenol vs Advil: What's the difference?
- CBD Oil: What are 9 Proven or Possible Health Benefits?
- Why does my child have leg pain or trouble walking after a fever?
- What are the rules for controlled drug refills?
- How much Tylenol can you take in a day?
- Can you take ibuprofen 800 mg with tramadol 50 mg?
- Aleve vs Advil: What's the difference?
- How long does ibuprofen take to work?
Drug information
Related support groups
- Vantrela ER (1 questions, 3 members)
- Pain (2,288 questions, 11,954 members)