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What is Myogesic used for?

Medically reviewed by Sally Chao, MD. Last updated on March 30, 2022.

Official answer


Myogesic is an oral analgesic used to treat pain and fever in adults. It comes in a tablet form. Each tablet contains two drugs:

Paracetamol is used as a pain reliever and fever reducer. Orphenadrine is used to relieve pain, and it also has anticholinergic effects, which can relax muscles. It’s typically prescribed along with rest, physical therapy and other measures to relieve muscle pain. It is not available in the United States.

The typical dosage of Myogesic is two tablets taken by mouth three times daily. Side effects include:

  • Sleepiness
  • Dizziness
  • Nausea
  • Feeling weak
  • Headache
  • Blurry vision
  • Dry mouth
  • Increased pressure in the eye
  • Dilation of the pupils
  • Urinary retention or hesitancy
  • Fast heart rate and palpitations
  • Constipation

Myogesic is available in Oman and may be available in other non-U.S. countries.

In the United States, similar drugs include:

Orphenadrine citrate (without acetaminophen) is available by prescription. It comes in an extended-release tablet and an injectable form. Typical dosages are:

  • One 100 mg tablet taken twice daily (once in the morning and once in the evening) as needed for pain.
  • 2 mL (60 mg) given intravenously or intramuscularly every 12 hours as needed for pain. The brand name, Norflex, is no longer on the market.

Orphengesic Forte is available by prescription in the U.S. It’s similar to Myogesic, but contains aspirin and caffeine instead of paracetamol. Each Orphengesic Forte tablet has:

  • 50 mg orphenadrine citrate
  • 770 mg aspirin
  • 60 mg caffeine

The typical adult dosage is 1/2 to 1 tablet taken by mouth 3 to 4 times daily for pain. Side effects are similar to those listed above for Myogesic. It’s not recommended for use in children under 12 years of age.

  1. Myogesic to relieve muscle pain. Available at: [Accessed March 18, 2022].
  2. National Institutes of Health (NIH). Orphenadrine Citrate Extended-Release Tablets 100 mg. December 27, 2019. Available at: [Accessed March 18, 2022].
  3. Kulud Pharmacy. Myogesic 20 tablets. Available at: [Accessed March 18, 2022].
  4. Myogesic. 2022. Available at: [Accessed March 18, 2022].
  5. National Institutes of Health (NIH). Orphenadrine Citrate injection. July 20, 2016. Available at: [Accessed March 18, 2022].
  6. Orphenadrine. February 28, 2022. Available at: [Accessed March 28, 2022].
  7. National Institutes of Health (NIH). Orphengesic forte tablets (Orphenadrine Citrate, Aspirin and Caffeine tablets 50 mg/ 770mg/ 60 mg USP). April 28, 2021. Available at: [Accessed March 18, 2022].
  8. Orphengesic Forte. May 31, 2021. Available at: [Accessed March 28, 2022].

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