Does Lupron Depot need to be refrigerated?

Q: Does Lupron Depot need to be refrigerated?

Before reconstitution, Lupron Depot for treatment of prostate cancer can be stored in its original container at room temperature (77°F [25°C]), with a range between 59°F to 86°F [15°C to 30°C]). Once Lupron Depot is reconstituted, inject the suspension immediately. Discard if not used within two hours, because Lupron Depot does not contain a preservative.

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Dec 6, 2024.

Official Answer by Drugs.com

Lupron Depot is injected by a healthcare provider to treat prostate cancer. Before reconstitution, Lupron Depot can be stored in its original container at room temperature (77°F [25°C], with a range between 59°F to 86°F [15°C to 30°C]). Keep the carton away from heat and moisture. Once Lupron Depot is reconstituted, inject the suspension immediately. Discard if not used within two hours, because Lupron Depot does not contain a preservative.

Learn more: How do you inject Lupron Depot for prostate cancer?

Lupron Depot is a gonadotropin releasing hormone (GnRH) agonist hormone therapy used for the palliative treatment (to relieve pain and other symptoms) of advanced prostate cancer. Your doctor may recommend you use this medicine long-term.

Lupron Depot is incorporated in a specialized powder formulation and is only injected by your doctor. This medicine is prepared before injection with a liquid (diluent) that is supplied in the package. You will receive this injection at your doctor’s office, a clinic or hospital.

Lupron Depot is injected into a muscle of your upper arm, upper thigh or buttocks either once every month, or once every 3, 4 or 6 months for the treatment of prostate cancer. Depot formulations continuously release medicine into your body over a certain period of time.

Prior to administration of Lupron, healthcare providers should review the illustrated directions for reconstitution and use here.

This is not all the information you need to know about Lupron Depot for safe and effective use. Review the full Lupron Depot information here, and discuss this and any questions you have with your doctor or other health care provider.

References

Lupron Depot (leuprolide acetate for depot suspension). AbbVie Inc. North Chicago, Ill. Revised March 2019. Accessed Dec. 16, 2020 at https://www.rxabbvie.com/pdf/lupronuro_pi.pdf

How long should you take Lupron for prostate cancer?

Patients treated with Lupron Depot (leuprolide acetate) for prostate cancer usually continue treatment upon development of castration-resistant prostate cancer, whether it has spread beyond the prostate (metastatic) or not. Continue reading

Are Lupron Depot and Eligard the same drug?

Lupron Depot and Eligard are brand name medicines that both contain the active ingredient leuprolide acetate. Both Lupron Depot and Eligard are prescribed to treat the symptoms of advanced prostate cancer. Lupron Depot is also approved to treat endometriosis, uterine fibroids, or central precocious puberty (CPP) in children (early puberty). Continue reading

Can you get pregnant on Lupron Depot?

Yes, you may still become pregnant if you are using Lupron Depot. Lupron Depot is not a method of birth control. Even though you may not have a period, unprotected intercourse could result in pregnancy. You should use a reliable non-hormonal birth control such as condoms, a diaphragm with contraceptive jelly, or a copper IUD to prevent pregnancy. Lupron Depot can cause harm to an unborn child. Contact your doctor right away if you think you are pregnant. Continue reading

Does Lupron Depot need to be refrigerated?

Read next

How long should you take Lupron for prostate cancer?

Are Lupron Depot and Eligard the same drug?

Can you get pregnant on Lupron Depot?

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