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How long does Suboxone withdrawal last?

Medically reviewed by Carmen Pope, BPharm. Last updated on March 28, 2025.

Official Answer by Drugs.com

Suboxone contains buprenorphine and naloxone and it has become one of the preferred treatments for opioid addiction. It is usually taken once a day.

Buprenorphine is a partial opioid agonist. This means it does not activate opioid receptors to the same extent as full agonists (such oxycodone, heroin or methadone), but it does block them, preventing other opioids from binding to these receptors.

Buprenorphine is a drug that has a ceiling, or maximum effect when it is given to people who have taken opioids before. This means that even if you take more buprenorphine, once you get past a certain dosage, you won’t see any increase in effects.

Despite its effectiveness, Suboxone can also be addictive. And because it occupies opioid receptors, it can produce similar withdrawal effects if quit “cold turkey”.

Symptoms of Suboxone withdrawal last approximately one month although this may vary depending on the duration of use and dosage of Suboxone, if the Suboxone was mixed with other drugs, such as alcohol, and the presence of other medical conditions or mental health disorders. Withdrawal symptoms generally follow this pattern:

Persistent drug cravings mean that users have a high risk of relapse a month out from stopping Suboxone. Always keep in touch with your detox therapist during this time.

Related questions

What are the symptoms of Suboxone withdrawal?

Symptoms of Suboxone withdrawal are similar to withdrawal symptoms from other opioids and include:

How can Suboxone withdrawal symptoms be reduced?

Suboxone should be tapered off slowly under the guidance of a health professional.

This involves slowly reducing the dosage of Suboxone over several weeks or months until you are no longer taking the drug. Other medications, such as clonidine, may be given to ease withdrawal symptoms.

There is little evidence to show that rapid detox (withdrawal over three days) is better at minimizing withdrawal symptoms and it may even be dangerous.

References

Read next

What happens if you take opiates on Suboxone?

If you use opiates while on Suboxone (a combination of buprenorphine and naloxone), the strong effects or “high” of the opiates will be dulled or blocked. Continue reading

How long should you wait before taking Suboxone?

You typically have to wait 12-24 hours after last using short acting opioids before you start taking Suboxone as a treatment for opioid use disorder. The exact length of time depends on the type of opioid used. Continue reading

Does Suboxone help with pain?

Suboxone is sometimes used “off-label” by doctors to help with acute or chronic pain in certain patients. However, Suboxone is is only approved by the FDA to treat narcotic (opiate) addiction (opioid use disorder). “Off-label" use of a drug refers to when a doctor prescribes a medicine for a different purpose than those formally approved by the FDA and found in the package labeling. Continue reading

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