How long does it take Ocrevus to work?
Ocrevus has some effect at reducing disability progression within about 12 weeks; however, it may take at least 6 months or possibly longer for the full effects to be seen. Trials of up to 96 weeks (almost 2 years) duration have shown that:
- The number of patients with disability progression was significantly lower with Ocrevus compared with REBIF (interferon beta-1a) at 12 weeks (9.1% of those prescribed Ocrevus vs. 13.6% of those prescribed REBIF), and 24 weeks (6.9% vs. 10.5%)
- 82% to 83% of people taking Ocrevus were relapse-free after 24 weeks compared to 71% to 72% of those taking REBIF
- People taking Ocrevus had 46% to 47% fewer relapses a year than people prescribed REBIF.
References
- Ocrevus (ocrelizumab) 05/2020 Genentech, Inc. https://www.drugs.com/pro/ocrevus.html
- Ocrevus. National Multiple Sclerosis Society. 2020 https://www.nationalmssociety.org/Treating-MS/Medications/Ocrevus#:~:text=Ocrevus%20is%20approved%20by%20the,primary%20progressive%20MS%20in%20adults.
- Hauser SL, Bar-Or A, Comi G, et al. Ocrelizumab versus Interferon Beta-1a
in Relapsing Multiple Sclerosis. N Engl J Med 2017;376:221-34.
DOI: 10.1056/NEJMoa1601277
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Is Kesimpta better than Ocrevus?
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Ocrevus is the only one of the two drugs approved to treat primary progressive multiple sclerosis Continue reading
How much does Ocrevus cost?
Ocrevus costs approximately $20,769 for one 300 mg/10mL vial depending on the pharmacy you visit and based on using the Drugs.com discount card. Most people do not pay for the full cost of Ocrevus. This price is for cash paying customers and is not valid with insurance plans. People with commercial or private insurance may be eligible for Ocrevus Co-Pay assistance and pay as little as $0 per infusion. Co-pay assistance is provided up to $1,500 per calendar year in the first year and up to $1,000 each calendar year after. Continue reading
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