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How soon can you start chemo after port placement?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on May 27, 2025.

Official Answer by Drugs.com

Chemotherapy can typically begin within a few days to 2 weeks after port placement, depending on factors like healing progress and treatment urgency. While same-day chemotherapy is possible in some cases, most healthcare providers recommend a short waiting period to ensure proper recovery and port functionality. A chemotherapy port is a critical tool for safe and efficient chemotherapy administration, and allows patients to receive medications with less needle sticks.

What Is a Chemo Port?

A chemo port (also called a port-a-cath or mediport) is a small, implantable device placed under the skin, usually in the upper chest. It consists of:

This device allows safe delivery of chemotherapy, blood draws, intravenous (IV) fluids, imaging contrast, and other medications without repeated needle sticks. Ports can remain in place for months or years and are removed after treatment completion.

Why Is There a Waiting Period After Port Placement?

Starting chemo too soon after port placement can increase complication risks. A brief waiting period (typically 2 days to 2 weeks) is recommended to:

Besides allowing the port time to heal, other factors that determine when chemotherapy can be started through the port include the type and stage of cancer and the type of medications being administered.

Can Chemotherapy Start Immediately After Port Placement?

In urgent cases, chemotherapy may start the same day as port placement, but this is less common and requires close monitoring. This decision is always made by the oncology team based on clinical need.

What Factors Affect When You Can Start Chemo?

There are several factors that affect how soon you can begin chemo after port placement, including:

How Is the Port Checked Before Starting Chemotherapy?

After placement of the port, it should be assessed to check for proper function and healing. Some of the following strategies may be used to check the port before starting chemo treatments:

Even after the initial placement, ports should be frequently checked for inflammation or other signs of infection.

Summary

Port placement streamlines chemotherapy delivery, but timing depends on individualized medical evaluation. Most patients may begin chemo within a few days to 2 weeks after port placement, but there are several factors to consider first. Always consult your oncology team to determine the safest schedule for your treatment plan.

References
  1. City of Hope. 2024. Chemotherapy Port. Accessed on May 27, 2025 at https://www.cancercenter.com/treatment-options/ports-and-catheters/chemo-port
  2. Kolikof, J., et. al. Updated 2025. Central Venous Catheter Insertion. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Accessed on May 27, 2025 at https://www.ncbi.nlm.nih.gov/books/NBK557798/
  3. Mountain View Surgical Associates. 2024. How Soon Can You Start Chemo After Port Placement? Accessed on May 27, 2025 at https://mtnviewsurgical.com/how-soon-can-you-start-chemo-after-port-placement/
  4. National Cancer Institute. NCI Dictionary of Cancer Terms: port-a-cath. Accessed on May 27, 2025 at https://www.cancer.gov/publications/dictionaries/cancer-terms/def/port-a-cath
  5. Ozdemir, N. Y., et. al. 2009. It appears to be safe to start chemotherapy on the day of implantation through subcutaneous venous port catheters in inpatient setting. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 17(4), 399–403. https://doi.org/10.1007/s00520-008-0498-x
  6. Teichgräber, U. K., et. al. 2011. Central venous port systems as an integral part of chemotherapy. Deutsches Arzteblatt international, 108(9), 147–154. https://doi.org/10.3238/arztebl.2011.0147

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