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What is the difference between Ogivri and Herceptin?

Medically reviewed by Drugs.com. Last updated on Sep 16, 2019.

Official Answer

by Drugs.com

Ogivri (trastuzumab-dkst) is a biosimilar to Herceptin (trastuzumab).

A biosimilar is a biological product that is FDA-approved and highly similar to a biologic already FDA-approved with no clinically meaningful differences in terms of safety and effectiveness from the reference product.

What Are Biosimilars? Top Facts You May Not Know

Ogivri and Herceptin are both used for the treatment of patients with HER2+ breast cancer or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma).

Ogivri has not been approved as an interchangeable biosimilar, meaning the pharmacist cannot substitute Ogivri for Herceptin without consulting the prescriber. Note that pharmacy laws and practices vary from state to state.

For more information, see Comparing Ogivri vs Herceptin

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