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How long does it take for Jaypirca to work?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on March 31, 2025.

Official Answer by Drugs.com

Jaypirca (pirtobrutinib) begins working soon after you start taking it, but the full effects may take a few months to appear. In clinical studies, some patients experienced tumor shrinkage as early as:

Jaypirca for Chronic Lymphocytic Leukemia (CLL)

In a clinical trial of adult patients who had received at least two prior treatments:

Jaypirca for Mantle Cell Lymphoma (MCL)

In a clinical trial of adults with MCL who had received at least two prior treatments:

How Does Jaypirca Work?

Jaypirca is a BTK inhibitor. BTK is a protein that signals activation of cancerous B-cells to multiply. By blocking BTK, Jaypirca stops cancer cells from multiplying and spreading in the body.

This is not all the information you need to know about Jaypirca (pirtobrutinib) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

References

Jaypirca [package insert]. Updated June 2024. Eli Lilly and Company. Accessed August 6, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bd551845-0878-49a4-860f-839b83f6b801

jaypirca.lilly.com. Jaypirca for CLL. n.d. Accessed August 6, 2024 at https://jaypirca.lilly.com/jaypirca-for-cll

jaypirca.lilly.com. Jaypirca for MCL. n.d. Accessed August 6, 2024 at https://jaypirca.lilly.com/jaypirca-for-mcl

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