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How does the drug Lokelma work?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on June 9, 2020.

Official Answer


Lokelma (sodium zirconium cyclosilicate) is an insoluble, non-absorbed sodium zirconium silicate agent that binds to potassium in the blood and acts as a highly selective potassium-removing agent.

It is used to treat high potassium (hyperkalemia) in adults. Hyperkalemia is associated with common conditions including chronic kidney disease, heart failure and diabetes.

Lokelma is available as a powder for oral suspension.

Drug Information

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