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Alpha-1-Proteinase Inhibitor, Human


Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Replacement therapy

Chemical Name

Human α-1-proteinase inhibitor is a plasma protein fraction containing mainly human α-1-proteinase inhibitor (also known as human α-1-antitrypsin or α-1-antiproteinase). Human α-1-proteinase inhibitor is a glycoprotein existing in isoforms with different (Ph. Eur.)

Foreign Names

  • Alpha-1-Proteinasi inhibitor humanum (Latin)
  • Alpha-1-Proteinase-Inhibitor vom Menschen (German)
  • Inhibiteur humain de la protéinase alpha-1 (French)

Generic Names

  • A₁-PI (IS)
  • A1AT (IS)
  • A1PI (IS)
  • AAT (IS)
  • Alpha₁-Antiproteinase (IS: human)
  • Alpha₁-Antitrypsin (IS: human)
  • Alpha₁-Protease inhibitor (IS)
  • α₁-Antiprotease (IS)
  • α₁-Antitrypsin (IS)
  • α₁-Trypsin inhibitor (IS)
  • Prolastin (IS)
  • α-1-Proteinasi inhibitor humanum (PH: Ph. Eur. 8)
  • Human α-1-proteinase inhibitor (PH: Ph. Eur. 8)

Brand Names

  • Alfalastin
    LFB, France
  • Aralast
    Baxter, United States; Baxter Arg., Argentina
  • Glassia
    Baxter Healthcare, United States; Kamada Ltd., Israel
  • Prolastin
    Demo, Greece; Grifols, Austria; Grifols, Germany; Grifols, Netherlands; Grifols, Poland; Grifols, Portugal; Grifols Italia, Italy; Vifor, Switzerland
  • Prolastin C
    Grifols, Canada; Talecris, United States; Tuteur, Argentina
  • Prolastina
    Crucell, Spain; Grifols, Norway; Grifols Deutschland, Denmark; Grifols Nordic, Finland; Grifols Nordic, Sweden
  • Pulmolast
    Lamepro, Belgium
  • Respreeza
    CSL Behring, Switzerland; CSL Behring, Germany; CSL Behring UK, United Kingdom
  • Trypsan
    Grifols Chile, Chile
  • Trypsone
    Grifols, Spain
  • Zemaira
    CSL Behring, United States


ISInofficial Synonym
PHPharmacopoeia Name
Ph. Eur.European Pharmacopoeia

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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