Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- desirudin
- Kengreal (cangrelor)
Interactions between your drugs
desirudin cangrelor
Applies to: desirudin, Kengreal (cangrelor)
MONITOR CLOSELY: Concomitant use of cangrelor with anticoagulants, thrombolytic agents, or other antiplatelet agents may theoretically increase the risk of bleeding. According to the manufacturer, cangrelor has been formally studied with unfractionated heparin and aspirin in healthy study subjects with no evidence of a pharmacokinetic or pharmacodynamic interaction. In clinical trials, cangrelor has been coadministered with bivalirudin, low molecular weight heparin, clopidogrel, prasugrel, and ticagrelor without clinically detectable interactions.
MANAGEMENT: Caution is recommended if cangrelor must be used in patients treated with other agents that alter hemostasis. Patients should be monitored for potentially increased bleeding complications.
References (2)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- (2015) "Product Information. Kengreal (cangrelor)." The Medicines Company
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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