Drug Interaction Report

Using colesevelam (sometimes called a "bile acid sequestrant") together with ezetimibe may decrease the effects of ezetimibe. These two medications are often used together to treat high cholesterol, but may need to be taken at different times. In general, ezetimibe should be administered at least 2 hours before or 4 hours after colesevelam. You may need additional blood work to ensure that this combination is working. Talk to your healthcare provider if you have any questions. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.