Drug Interaction Report
8 potential interactions and/or warnings found for the following 2 drugs:
- cholestyramine
- Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
Interactions between your drugs
hydrALAZINE hydroCHLOROthiazide
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine), Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
HydroCHLOROthiazide may add to the blood pressure lowering effects of hydrALAZINE. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Contact your doctor if you experience dizziness, weakness, fatigue, lightheadedness, headache, flushing, fainting, or a rapid pulse or heart rate. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydrALAZINE reserpine
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine), Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
Reserpine may add to the blood pressure lowering effects of hydrALAZINE. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Contact your doctor if you experience dizziness, weakness, fatigue, lightheadedness, headache, flushing, fainting, or a rapid pulse or heart rate. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
cholestyramine hydroCHLOROthiazide
Applies to: cholestyramine, Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
Cholestyramine may interfere with the absorption of hydroCHLOROthiazide when these medications are taken at the same time. This may reduce the blood levels and effects of hydroCHLOROthiazide. To prevent or minimize the interaction, hydroCHLOROthiazide should be taken at least 1 to 2 hours before or 4 to 6 hours after the cholestyramine dose. Contact your doctor if your condition changes or your symptoms worsen during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydroCHLOROthiazide reserpine
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine), Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
Before taking hydroCHLOROthiazide, tell your doctor if you also use reserpine. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take reserpine at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
hydrALAZINE food
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
HydrALAZINE and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydroCHLOROthiazide food
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
HydroCHLOROthiazide and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
reserpine food
Applies to: Hydrap-ES (hydralazine / hydrochlorothiazide / reserpine)
Reserpine and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
cholestyramine food
Applies to: cholestyramine
Cholestyramine may interfere with the absorption of certain vitamins such as A, D, E and K. Therefore, it is recommended that you take multivitamin with minerals at least 1 hour before or 4 to 6 hours after cholestyramine to minimize the risk of interaction. Talk to your doctor or pharmacist if you have questions on how to take these or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Leqvio
Leqvio is used in adults with primary hyperlipidemia to reduce low-density lipoprotein (LDL-C) ...
Repatha
Repatha (evolocumab) is a PCSK9 inhibitor used to lower high cholesterol alongside dietary changes ...
Botox
Botox is used to treat chronic migraines, excessive sweating, bladder conditions, eye muscle ...
Lipitor
Lipitor is used to treat high cholesterol. Learn about side effects, interactions and indications.
Crestor
Crestor (rosuvastatin) is used to treat high cholesterol and high triglycerides in the blood ...
Zetia
Zetia (ezetimibe) is used to treat high cholesterol. Includes Zetia side effects, interactions and ...
Zocor
Zocor (simvastatin) reduces low-density lipoprotein cholesterol and total cholesterol in the blood ...
TriCor
Tricor (fenofibrate) helps reduce cholesterol and triglycerides (fatty acids) in the blood ...
Mevacor
Mevacor is used for high cholesterol, high cholesterol, familial heterozygous ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.