Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- hyaluronidase / nivolumab
- sodium thiosalicylate
Interactions between your drugs
sodium thiosalicylate hyaluronidase
Applies to: sodium thiosalicylate, hyaluronidase / nivolumab
Larger amounts of hyaluronidase may be required to achieve equivalent dispersing effects if patients are concomitantly receiving large doses of salicylates, cortisone, ACTH, estrogens, or antihistamines. These drugs may render tissues partially resistant to the dispersing action of hyaluronidase.
References (3)
- (2004) "Product Information. Vitrase (hyaluronidase)." Bausch and Lomb Americas, Inc.
- (2018) "Product Information. Hylenex (hyaluronidase)." Halozyme Therapeutics
- (2023) "Product Information. Vyvgart Hytrulo (efgartigimod alfa-hyaluronidase)." argenx US Inc.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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