Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- bupivacaine / dexamethasone / epinephrine
- colesevelam
Interactions between your drugs
dexAMETHasone colesevelam
Applies to: bupivacaine / dexamethasone / epinephrine, colesevelam
Bile acid binding resins such as cholestyramine, colestipol, and colesevelam may interfere with the absorption of dexAMETHasone and reduce its levels in the bloodstream. This may make the medication less effective in treating your condition. To minimize the possibility of interaction, it is recommended that you separate the dosing times of the bile acid binding resin and other oral medications. If you are taking cholestyramine or colestipol, you should take dexAMETHasone at least 1 hour before or 4 to 6 hours after the cholestyramine or colestipol dose. If you are taking colesevelam, you should take dexAMETHasone at least 4 hours before the colesevelam dose, or separate the dosing times by as much as possible if a 4 hour interval is not achievable. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
EPINEPHrine food
Applies to: bupivacaine / dexamethasone / epinephrine
Both EPINEPHrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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